Orthotopic Implantation Achieves Better Engraftment and Faster Growth Than Subcutaneous Implantation in Breast Cancer Patient-Derived Xenografts

Patient-Derived Xenograft (PDX) is now accepted as a murine model that better mimics human cancer when compared to a conventional cancer cell-line inoculation model. Some claim the advantage of orthotopic site implantation of patient tumor (OS) over ectopic implantation into the subcutaneous space (...

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Veröffentlicht in:	Journal of mammary gland biology and neoplasia 2020-03, Vol.25 (1), p.27-36
Hauptverfasser:	Okano, Maiko, Oshi, Masanori, Butash, Ali, Okano, Ichiro, Saito, Katsuharu, Kawaguchi, Tsutomu, Nagahashi, Masayuki, Kono, Koji, Ohtake, Toru, Takabe, Kazuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Breast cancer Cancer Research ErbB-2 protein Inoculation Medicine Medicine & Public Health Oncology Transplantation Transplants & implants Tumors Xenografts
Online-Zugang:	Volltext
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