High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis
Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patient...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical medicine 2020-03, Vol.9 (3), p.848 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 3 |
| container_start_page | 848 |
| container_title | Journal of clinical medicine |
| container_volume | 9 |
| creator | Rosier, Laurent Zouaghi, Amir Barré, Valentin Martins, Raphaël Probst, Vincent Marijon, Eloi Sadoul, Nicolas Chauveau, Samuel Da Costa, Antoine Badoz, Marc Peyrol, Michael Barraud, Jérémie Massoullie, Grégoire Eschalier, Romain Espinosa, Madeline Lesaffre, François Garcia, Rodrigue Degand, Bruno Noël, Antoine Mansourati, Jacques Extramiana, Fabrice Algalarrondo, Vincent Devilliers, Hervé Cottin, Yves Gandjbakhch, Estelle Guenancia, Charles |
| description | Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan-Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode. |
| doi_str_mv | 10.3390/jcm9030848 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7141537</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2641159819</sourcerecordid><originalsourceid>FETCH-LOGICAL-c506t-d72661bd1e2db297300f84a87b806ce8ad8b38bd32b1ed66867a37fe131ff61a3</originalsourceid><addsrcrecordid>eNpdkdtKAzEQhoMoKuqNDyAL3qhQzalJ9kYoolaoKPVwG7LJrJu6B012hb69W1qPc5Mh882fyfwI7RN8yliKz2a2SjHDiqs1tE2xlAPMFFv_lW-hvRhnuA-lOCVyE20xSjlPFdtG92P_UiRTH1-TJk8eutgaX4NLnqFug7ddaUIyCqGYt0XlTTIF24UAtYVklLfQ12zXQnI7b6wJzrc-7qKN3JQR9lbnDnq6uny8GA8md9c3F6PJwA6xaAdOUiFI5ghQl9FUMoxzxY2SmcLCgjJOZUxljtGMgBNCCWmYzIEwkueCGLaDzpe6b11WgbOLeU2p34KvTJjrxnj9t1L7Qr80H1oSToZM9gLHS4HiX9t4NNGLO0xTnlKJP0jPHq0eC817B7HVlY8WytLU0HRRU6YEVZhT3qOH_9BZ04W6X4WmghMyTBVJe-pkSdnQxBgg_56AYL3wVf_42sMHv7_6jX65yD4BMgedEw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2641159819</pqid></control><display><type>article</type><title>High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis</title><source>PubMed Central Open Access</source><source>MDPI - Multidisciplinary Digital Publishing Institute</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Rosier, Laurent ; Zouaghi, Amir ; Barré, Valentin ; Martins, Raphaël ; Probst, Vincent ; Marijon, Eloi ; Sadoul, Nicolas ; Chauveau, Samuel ; Da Costa, Antoine ; Badoz, Marc ; Peyrol, Michael ; Barraud, Jérémie ; Massoullie, Grégoire ; Eschalier, Romain ; Espinosa, Madeline ; Lesaffre, François ; Garcia, Rodrigue ; Degand, Bruno ; Noël, Antoine ; Mansourati, Jacques ; Extramiana, Fabrice ; Algalarrondo, Vincent ; Devilliers, Hervé ; Cottin, Yves ; Gandjbakhch, Estelle ; Guenancia, Charles</creator><creatorcontrib>Rosier, Laurent ; Zouaghi, Amir ; Barré, Valentin ; Martins, Raphaël ; Probst, Vincent ; Marijon, Eloi ; Sadoul, Nicolas ; Chauveau, Samuel ; Da Costa, Antoine ; Badoz, Marc ; Peyrol, Michael ; Barraud, Jérémie ; Massoullie, Grégoire ; Eschalier, Romain ; Espinosa, Madeline ; Lesaffre, François ; Garcia, Rodrigue ; Degand, Bruno ; Noël, Antoine ; Mansourati, Jacques ; Extramiana, Fabrice ; Algalarrondo, Vincent ; Devilliers, Hervé ; Cottin, Yves ; Gandjbakhch, Estelle ; Guenancia, Charles</creatorcontrib><description>Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan-Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm9030848</identifier><identifier>PMID: 32244983</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bernard, Claude (1813-1878) ; Cardiac arrhythmia ; Cardiovascular disease ; Clinical medicine ; Defibrillators ; Edema ; Family medical history ; Heart ; Hospitals ; Life Sciences ; Magnetic resonance imaging ; Medical imaging ; Myocarditis ; Normal distribution ; Patients ; Sarcoidosis</subject><ispartof>Journal of clinical medicine, 2020-03, Vol.9 (3), p.848</ispartof><rights>2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c506t-d72661bd1e2db297300f84a87b806ce8ad8b38bd32b1ed66867a37fe131ff61a3</citedby><cites>FETCH-LOGICAL-c506t-d72661bd1e2db297300f84a87b806ce8ad8b38bd32b1ed66867a37fe131ff61a3</cites><orcidid>0000-0001-7227-3428 ; 0000-0002-9547-0835 ; 0000-0003-3051-2560 ; 0000-0002-3554-7714 ; 0000-0002-5176-5121 ; 0000-0002-4199-4019 ; 0000-0002-4846-5021 ; 0000-0002-6697-7194 ; 0000-0003-3302-9988</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141537/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141537/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32244983$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.sorbonne-universite.fr/hal-02949270$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Rosier, Laurent</creatorcontrib><creatorcontrib>Zouaghi, Amir</creatorcontrib><creatorcontrib>Barré, Valentin</creatorcontrib><creatorcontrib>Martins, Raphaël</creatorcontrib><creatorcontrib>Probst, Vincent</creatorcontrib><creatorcontrib>Marijon, Eloi</creatorcontrib><creatorcontrib>Sadoul, Nicolas</creatorcontrib><creatorcontrib>Chauveau, Samuel</creatorcontrib><creatorcontrib>Da Costa, Antoine</creatorcontrib><creatorcontrib>Badoz, Marc</creatorcontrib><creatorcontrib>Peyrol, Michael</creatorcontrib><creatorcontrib>Barraud, Jérémie</creatorcontrib><creatorcontrib>Massoullie, Grégoire</creatorcontrib><creatorcontrib>Eschalier, Romain</creatorcontrib><creatorcontrib>Espinosa, Madeline</creatorcontrib><creatorcontrib>Lesaffre, François</creatorcontrib><creatorcontrib>Garcia, Rodrigue</creatorcontrib><creatorcontrib>Degand, Bruno</creatorcontrib><creatorcontrib>Noël, Antoine</creatorcontrib><creatorcontrib>Mansourati, Jacques</creatorcontrib><creatorcontrib>Extramiana, Fabrice</creatorcontrib><creatorcontrib>Algalarrondo, Vincent</creatorcontrib><creatorcontrib>Devilliers, Hervé</creatorcontrib><creatorcontrib>Cottin, Yves</creatorcontrib><creatorcontrib>Gandjbakhch, Estelle</creatorcontrib><creatorcontrib>Guenancia, Charles</creatorcontrib><title>High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan-Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode.</description><subject>Bernard, Claude (1813-1878)</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Clinical medicine</subject><subject>Defibrillators</subject><subject>Edema</subject><subject>Family medical history</subject><subject>Heart</subject><subject>Hospitals</subject><subject>Life Sciences</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Myocarditis</subject><subject>Normal distribution</subject><subject>Patients</subject><subject>Sarcoidosis</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkdtKAzEQhoMoKuqNDyAL3qhQzalJ9kYoolaoKPVwG7LJrJu6B012hb69W1qPc5Mh882fyfwI7RN8yliKz2a2SjHDiqs1tE2xlAPMFFv_lW-hvRhnuA-lOCVyE20xSjlPFdtG92P_UiRTH1-TJk8eutgaX4NLnqFug7ddaUIyCqGYt0XlTTIF24UAtYVklLfQ12zXQnI7b6wJzrc-7qKN3JQR9lbnDnq6uny8GA8md9c3F6PJwA6xaAdOUiFI5ghQl9FUMoxzxY2SmcLCgjJOZUxljtGMgBNCCWmYzIEwkueCGLaDzpe6b11WgbOLeU2p34KvTJjrxnj9t1L7Qr80H1oSToZM9gLHS4HiX9t4NNGLO0xTnlKJP0jPHq0eC817B7HVlY8WytLU0HRRU6YEVZhT3qOH_9BZ04W6X4WmghMyTBVJe-pkSdnQxBgg_56AYL3wVf_42sMHv7_6jX65yD4BMgedEw</recordid><startdate>20200320</startdate><enddate>20200320</enddate><creator>Rosier, Laurent</creator><creator>Zouaghi, Amir</creator><creator>Barré, Valentin</creator><creator>Martins, Raphaël</creator><creator>Probst, Vincent</creator><creator>Marijon, Eloi</creator><creator>Sadoul, Nicolas</creator><creator>Chauveau, Samuel</creator><creator>Da Costa, Antoine</creator><creator>Badoz, Marc</creator><creator>Peyrol, Michael</creator><creator>Barraud, Jérémie</creator><creator>Massoullie, Grégoire</creator><creator>Eschalier, Romain</creator><creator>Espinosa, Madeline</creator><creator>Lesaffre, François</creator><creator>Garcia, Rodrigue</creator><creator>Degand, Bruno</creator><creator>Noël, Antoine</creator><creator>Mansourati, Jacques</creator><creator>Extramiana, Fabrice</creator><creator>Algalarrondo, Vincent</creator><creator>Devilliers, Hervé</creator><creator>Cottin, Yves</creator><creator>Gandjbakhch, Estelle</creator><creator>Guenancia, Charles</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7227-3428</orcidid><orcidid>https://orcid.org/0000-0002-9547-0835</orcidid><orcidid>https://orcid.org/0000-0003-3051-2560</orcidid><orcidid>https://orcid.org/0000-0002-3554-7714</orcidid><orcidid>https://orcid.org/0000-0002-5176-5121</orcidid><orcidid>https://orcid.org/0000-0002-4199-4019</orcidid><orcidid>https://orcid.org/0000-0002-4846-5021</orcidid><orcidid>https://orcid.org/0000-0002-6697-7194</orcidid><orcidid>https://orcid.org/0000-0003-3302-9988</orcidid></search><sort><creationdate>20200320</creationdate><title>High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis</title><author>Rosier, Laurent ; Zouaghi, Amir ; Barré, Valentin ; Martins, Raphaël ; Probst, Vincent ; Marijon, Eloi ; Sadoul, Nicolas ; Chauveau, Samuel ; Da Costa, Antoine ; Badoz, Marc ; Peyrol, Michael ; Barraud, Jérémie ; Massoullie, Grégoire ; Eschalier, Romain ; Espinosa, Madeline ; Lesaffre, François ; Garcia, Rodrigue ; Degand, Bruno ; Noël, Antoine ; Mansourati, Jacques ; Extramiana, Fabrice ; Algalarrondo, Vincent ; Devilliers, Hervé ; Cottin, Yves ; Gandjbakhch, Estelle ; Guenancia, Charles</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c506t-d72661bd1e2db297300f84a87b806ce8ad8b38bd32b1ed66867a37fe131ff61a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Bernard, Claude (1813-1878)</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Clinical medicine</topic><topic>Defibrillators</topic><topic>Edema</topic><topic>Family medical history</topic><topic>Heart</topic><topic>Hospitals</topic><topic>Life Sciences</topic><topic>Magnetic resonance imaging</topic><topic>Medical imaging</topic><topic>Myocarditis</topic><topic>Normal distribution</topic><topic>Patients</topic><topic>Sarcoidosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rosier, Laurent</creatorcontrib><creatorcontrib>Zouaghi, Amir</creatorcontrib><creatorcontrib>Barré, Valentin</creatorcontrib><creatorcontrib>Martins, Raphaël</creatorcontrib><creatorcontrib>Probst, Vincent</creatorcontrib><creatorcontrib>Marijon, Eloi</creatorcontrib><creatorcontrib>Sadoul, Nicolas</creatorcontrib><creatorcontrib>Chauveau, Samuel</creatorcontrib><creatorcontrib>Da Costa, Antoine</creatorcontrib><creatorcontrib>Badoz, Marc</creatorcontrib><creatorcontrib>Peyrol, Michael</creatorcontrib><creatorcontrib>Barraud, Jérémie</creatorcontrib><creatorcontrib>Massoullie, Grégoire</creatorcontrib><creatorcontrib>Eschalier, Romain</creatorcontrib><creatorcontrib>Espinosa, Madeline</creatorcontrib><creatorcontrib>Lesaffre, François</creatorcontrib><creatorcontrib>Garcia, Rodrigue</creatorcontrib><creatorcontrib>Degand, Bruno</creatorcontrib><creatorcontrib>Noël, Antoine</creatorcontrib><creatorcontrib>Mansourati, Jacques</creatorcontrib><creatorcontrib>Extramiana, Fabrice</creatorcontrib><creatorcontrib>Algalarrondo, Vincent</creatorcontrib><creatorcontrib>Devilliers, Hervé</creatorcontrib><creatorcontrib>Cottin, Yves</creatorcontrib><creatorcontrib>Gandjbakhch, Estelle</creatorcontrib><creatorcontrib>Guenancia, Charles</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rosier, Laurent</au><au>Zouaghi, Amir</au><au>Barré, Valentin</au><au>Martins, Raphaël</au><au>Probst, Vincent</au><au>Marijon, Eloi</au><au>Sadoul, Nicolas</au><au>Chauveau, Samuel</au><au>Da Costa, Antoine</au><au>Badoz, Marc</au><au>Peyrol, Michael</au><au>Barraud, Jérémie</au><au>Massoullie, Grégoire</au><au>Eschalier, Romain</au><au>Espinosa, Madeline</au><au>Lesaffre, François</au><au>Garcia, Rodrigue</au><au>Degand, Bruno</au><au>Noël, Antoine</au><au>Mansourati, Jacques</au><au>Extramiana, Fabrice</au><au>Algalarrondo, Vincent</au><au>Devilliers, Hervé</au><au>Cottin, Yves</au><au>Gandjbakhch, Estelle</au><au>Guenancia, Charles</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2020-03-20</date><risdate>2020</risdate><volume>9</volume><issue>3</issue><spage>848</spage><pages>848-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>Acute myocarditis is associated with cardiac arrhythmia in 25% of cases; a third of these arrhythmias are ventricular tachycardia (VT) or ventricular fibrillation (VF). The implantation of a cardiac defibrillator (ICD) following sustained ventricular arrhythmia remains controversial in these patients. We sought to assess the risk of major arrhythmic ventricular events (MAEs) over time in patients implanted with an ICD following sustained VT/VF in the acute phase of myocarditis compared to those implanted for VT/VF occurring on myocarditis sequelae. Our retrospective observational study included patients implanted with an ICD following VT/VF during acute myocarditis or VT/VF on myocarditis sequelae, from 2007 to 2017, in 15 French university hospitals. Over a median follow-up period of 3 years, MAE occurred in 11 (39%) patients of the acute myocarditis group and 24 (60%) patients of the myocarditis sequelae group. Kaplan-Meier MAE rate estimates at one and three years of follow-up were 19% and 45% in the acute group, and 43% and 64% in the sequelae group. Patients who experienced sustained ventricular arrhythmias during acute myocarditis had a very high risk of VT/VF recurrence during follow-up. These results show that the risk of MAE recurrence remains high after resolution of the acute episode.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>32244983</pmid><doi>10.3390/jcm9030848</doi><orcidid>https://orcid.org/0000-0001-7227-3428</orcidid><orcidid>https://orcid.org/0000-0002-9547-0835</orcidid><orcidid>https://orcid.org/0000-0003-3051-2560</orcidid><orcidid>https://orcid.org/0000-0002-3554-7714</orcidid><orcidid>https://orcid.org/0000-0002-5176-5121</orcidid><orcidid>https://orcid.org/0000-0002-4199-4019</orcidid><orcidid>https://orcid.org/0000-0002-4846-5021</orcidid><orcidid>https://orcid.org/0000-0002-6697-7194</orcidid><orcidid>https://orcid.org/0000-0003-3302-9988</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2077-0383 |
| ispartof | Journal of clinical medicine, 2020-03, Vol.9 (3), p.848 |
| issn | 2077-0383 2077-0383 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7141537 |
| source | PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Bernard, Claude (1813-1878) Cardiac arrhythmia Cardiovascular disease Clinical medicine Defibrillators Edema Family medical history Heart Hospitals Life Sciences Magnetic resonance imaging Medical imaging Myocarditis Normal distribution Patients Sarcoidosis |
| title | High Risk of Sustained Ventricular Arrhythmia Recurrence After Acute Myocarditis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T05%3A16%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=High%20Risk%20of%20Sustained%20Ventricular%20Arrhythmia%20Recurrence%20After%20Acute%20Myocarditis&rft.jtitle=Journal%20of%20clinical%20medicine&rft.au=Rosier,%20Laurent&rft.date=2020-03-20&rft.volume=9&rft.issue=3&rft.spage=848&rft.pages=848-&rft.issn=2077-0383&rft.eissn=2077-0383&rft_id=info:doi/10.3390/jcm9030848&rft_dat=%3Cproquest_pubme%3E2641159819%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2641159819&rft_id=info:pmid/32244983&rfr_iscdi=true |