Prolactin-Responsive Circular RNA circHIPK3 Promotes Proliferation of Mammary Epithelial Cells from Dairy Cow

The highly expressed circHIPK3 is a circular RNA that has been previously reported to regulate the growth of human cells. In this study, we found an increased expression of circHIPK3 in bovine mammary epithelial cells treated with prolactin (PRL) in high-throughput sequencing data. Thus, we further...

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Veröffentlicht in:	Genes 2020-03, Vol.11 (3), p.336
Hauptverfasser:	Liu, Jia, Zhang, MoLan, Li, DeWei, Li, MengLu, Kong, LingHao, Cao, MengWen, Wang, YanHong, Song, ChengChuang, Fang, XingTang, Chen, Hong, Xu, Hu, Zhang, ChunLei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal lactation Animals Apoptosis Cattle Cell differentiation Cell growth Cell Proliferation Cholecystokinin Circular RNA Dairy cattle Epidermal growth factor Epithelial cells Epithelial Cells - metabolism Epithelial Cells - physiology Experiments Female Insulin Mammary gland Mammary Glands, Animal - cytology Mice Mice, Inbred C57BL Milk Next-generation sequencing Prolactin Prolactin - metabolism Ribonucleic acid RNA RNA Splicing Factors - genetics RNA Splicing Factors - metabolism RNA, Circular - genetics RNA, Circular - metabolism Signal Transduction Software STAT Transcription Factors - genetics STAT Transcription Factors - metabolism Stat5 protein Statistical analysis Western blotting
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