Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells

Metabolite exchange between stromal and tumor cells or among tumor cells themselves accompanies metabolic reprogramming in cancer including pancreatic adenocarcinoma (PDAC). Some tumor cells import and utilize lactate for oxidative energy production (reverse Warburg-metabolism) and the presence of t...

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Veröffentlicht in:Cancers 2020-03, Vol.12 (3), p.581
Hauptverfasser: Sandforth, Leontine, Ammar, Nourhane, Dinges, Lisa Antonia, Röcken, Christoph, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner
Format: Artikel
Sprache:eng
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