Adiponectin and Cognitive Decline

Adiponectin (ADPN) is a plasma protein secreted by adipose tissue showing pleiotropic effects with anti-diabetic, anti-atherogenic, and anti-inflammatory properties. Initially, it was thought that the main role was only the metabolism control. Later, ADPN receptors were also found in the central ner...

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Veröffentlicht in:	International journal of molecular sciences 2020-03, Vol.21 (6), p.2010
Hauptverfasser:	Rizzo, Maria Rosaria, Fasano, Renata, Paolisso, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Adiponectin Adiponectin - blood Adiponectin - metabolism Adiponectin - pharmacology Adipose tissue Adipose Tissue - metabolism Aging AMP-activated protein kinase AMP-Activated Protein Kinases - metabolism Anti-inflammatory agents Apoptosis Biomarkers Brain - drug effects C-reactive protein Central nervous system Central Nervous System - drug effects Chronic illnesses Cognitive ability Cognitive Dysfunction - metabolism Cytokines Cytotoxicity Dementia Dementia - metabolism Diabetes Diabetes mellitus Drug therapy Estrogens Estrogens - adverse effects Female Glucose Humans Hypothalamus Inflammation Insulin Insulin resistance Insulin Resistance - physiology Interleukin 6 Kinases Male Memory Memory - drug effects Menopause Menopause - physiology Metabolism Molecular weight Neurodegeneration Neurogenesis Neuroplasticity Neuroprotection Neurotoxicity Obesity Oxidative stress Post-menopause PPAR alpha Proteins Receptors, Adiponectin - metabolism Review Risk Factors Serum levels Signal Transduction Speech Disorders
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