Ganglioside GM3 Up-Regulate Chondrogenic Differentiation by Transform Growth Factor Receptors

Mesenchymal stem cells, also known as multipotent stromal progenitor cells, can differentiate into cells of mesodermal lineage. Gangliosides are sialic acid-conjugated glycosphingolipids that are believed to regulate cell differentiation and several signaling molecules. These molecules are localized...

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Veröffentlicht in:	International journal of molecular sciences 2020-03, Vol.21 (6), p.1967
Hauptverfasser:	Ryu, Jae-Sung, Seo, Sang Young, Jeong, Eun-Jeong, Kim, Jong-Yeup, Koh, Yong-Gon, Kim, Yong Il, Choo, Young-Kug
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Aggregates Apoptosis Cartilage Cartilage (articular) Cartilage diseases Cell culture Cell differentiation Cell growth Cell surface Chemical compounds Chondrogenesis Collagen Dehydrogenases Differentiation (biology) Ganglioside GM3 Gangliosides Gene expression Glycosaminoglycans Glycosphingolipids Growth factor receptors Growth factors Mesenchyme Pharmacology Phosphorylation Progenitor cells Signal transduction Smad protein Stem cells Studies Synovial membrane Toluidine blue Transforming growth factor-b
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