Silencing of lncRNA XIST inhibits non-small cell lung cancer growth and promotes chemosensitivity to cisplatin

Long noncoding RNAs (lncRNAs) play critical roles in tumour progression and metastasis. Emerging evidence indicates that the lncRNA X inactive-specific transcript (XIST) is dysregulated in several tumor types, including non-small cell lung cancer (NSCLC). However, in NSCLC and other cancers the onco...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2020-03, Vol.12 (6), p.4711-4726
Hauptverfasser:	Xu, Xiaohui, Zhou, Xiaoyun, Chen, Zhenju, Gao, Chao, Zhao, Luo, Cui, Yushang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - administration & dosage Apoptosis Carcinoma, Non-Small-Cell Lung - metabolism Cisplatin - administration & dosage Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - physiology Humans Research Paper RNA, Long Noncoding - metabolism Smad2 Protein - metabolism Tumor Cells, Cultured
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