Single Hepatocyte Hepatitis B Virus Transcriptional Landscape in HIV Coinfection

Abstract Background Hepatitis B virus (HBV) is a leading cause of liver failure and hepatocellular carcinoma. Approximately 10% of people with HIV also have HBV and are at higher risk of liver disease progression than in HBV monoinfection. Antivirals, common to HIV and HBV, suppress HBV DNA levels b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 2020-04, Vol.221 (9), p.1462-1469
Hauptverfasser:	Balagopal, Ashwin, Hwang, Hyon S, Grudda, Tanner, Quinn, Jeffrey, Sterling, Richard K, Sulkowski, Mark S, Thio, Chloe L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral agents Antiviral drugs Circular DNA Deoxyribonucleic acid DNA DNA, Circular - genetics DNA, Viral - genetics Gene regulation Hepatitis Hepatitis B Hepatitis B e Antigens - immunology Hepatitis B virus - physiology Hepatitis B, Chronic - virology Hepatocellular carcinoma Hepatocytes Hepatocytes - virology HIV HIV Infections - virology Human immunodeficiency virus Humans Immunology Infectious Diseases Life Sciences & Biomedicine Liver diseases Major and Brief Reports Male Microbiology Middle Aged Polymerase chain reaction Ribonucleic acid RNA Science & Technology Transcription Virus Replication - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!