High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase

The causative agent of severe acute respiratory syndrome (SARS) has been identified as a novel coronavirus, SARS-CoV. The main proteinase of SARS-CoV, 3CL pro, is an attractive target for therapeutics against SARS owing to its fundamental role in viral replication. We sought to identify novel inhibi...

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Veröffentlicht in:Chemistry & biology 2004-10, Vol.11 (10), p.1445-1453
Hauptverfasser: Blanchard, Jan E., Elowe, Nadine H., Huitema, Carly, Fortin, Pascal D., Cechetto, Jonathan D., Eltis, Lindsay D., Brown, Eric D.
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Sprache:eng
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