Sequence similarity and structural homologies are involved in the autoimmune response elicited by mouse hepatitis virus A59

The features of autoantibodies (autoAb) to liver fumarylacetoacetate hydrolase (FAH) elicited in mice infected with mouse hepatitis virus (MHV) were studied by ELISA and western-blot competition assays. All sera tested contained Ab to cryptic FAH epitopes according with results from western-blot tes...

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Veröffentlicht in:	Journal of autoimmunity 2004-09, Vol.23 (2), p.117-126
Hauptverfasser:	Mathieu, Patricia A., Gómez, Karina A., Coutelier, Jean-Paul, Retegui, Lilia A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - immunology Antigens, Viral - chemistry Antigens, Viral - immunology Autoantibodies - blood Autoantibodies - immunology Autoantibody Autoantigens - immunology Autoimmune Diseases - etiology Autoimmune Diseases - virology Autoimmune response Autoimmunity Binding, Competitive Biological and medical sciences Cross Reactions - immunology Cryptic epitopes DNA-Directed RNA Polymerases - chemistry DNA-Directed RNA Polymerases - immunology Female Fumarylacetoacetate hydrolase Fundamental and applied biological sciences. Psychology Fundamental immunology General aspects Hydrolases - chemistry Hydrolases - immunology Immunopathology Liver - enzymology Medical sciences Mice Mice, Inbred Strains Mouse hepatitis virus Murine hepatitis virus Murine hepatitis virus - immunology Sequence Homology, Amino Acid Structural Homology, Protein
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