Case Report: Successful Treatment of a Patient with Microfilaremic Dirofilariasis Using Doxycycline
We report the case of a 56-year-old woman with microfilaremic dirofilariasis due to , which is a very rare condition in humans. Of note, just one of six large-volume blood samples of this patient was positive for microfilariae. Polymerase chain reaction (PCR) and sequencing of the parasite gene dete...
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| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2020-04, Vol.102 (4), p.844-846 |
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| container_title | The American journal of tropical medicine and hygiene |
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| creator | Lechner, Arno M Gastager, Herbert Kern, Jan Marco Wagner, Birgit Tappe, Dennis |
| description | We report the case of a 56-year-old woman with microfilaremic dirofilariasis due to
, which is a very rare condition in humans. Of note, just one of six large-volume blood samples of this patient was positive for microfilariae. Polymerase chain reaction (PCR) and sequencing of the parasite gene determined the geographic origin of the causative helminth. The patient was treated successfully with doxycycline. This drug was chosen because of the patient's reluctance to the use of ivermectin and to provide an anthelmintic effect by targeting the bacterial endosymbiont
present in most filarial species. |
| doi_str_mv | 10.4269/ajtmh.19-0744 |
| format | Article |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Anti-Bacterial Agents - therapeutic use Antibiotics Case reports Clinical outcomes Dirofilaria repens Dirofilariasis - diagnostic imaging Dirofilariasis - therapy Doxycycline - therapeutic use Drug therapy Female Humans Middle Aged Parasites Parasitic diseases |
| title | Case Report: Successful Treatment of a Patient with Microfilaremic Dirofilariasis Using Doxycycline |
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