Novel coronavirus and severe acute respiratory syndrome
In today's Lancet, Joseph Peiris and colleagues provide strong evidence that SARS is associated with a novel coronavirus that has not been previously identified in human beings or animals, and begin the process of eliminating the many unknowns from this new syndrome (figure). The investigators...
Gespeichert in:
| Veröffentlicht in: | The Lancet (British edition) 2003-04, Vol.361 (9366), p.1312-1313 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1313 |
|---|---|
| container_issue | 9366 |
| container_start_page | 1312 |
| container_title | The Lancet (British edition) |
| container_volume | 361 |
| creator | Falsey, Ann R Walsh, Edward E |
| description | In today's Lancet, Joseph Peiris and colleagues provide strong evidence that SARS is associated with a novel coronavirus that has not been previously identified in human beings or animals, and begin the process of eliminating the many unknowns from this new syndrome (figure). The investigators used classic viral culture and serological techniques, as well as modern molecular genetic methods, to characterise and to determine the cause of the disease in 50 patients with SARS in Hong Kong. One of the strengths of their report, and an important means of establishing causality, is their analysis of specimens from control patients. None of 40 respiratory secretions from patients with other respiratory diseases contained coronavirus RNA, and none of 200 serum samples from blood donors had serum antibody to this new coronavirus. These findings significantly strengthen the tentative aetiological association reported by other investigators from the Centers for Disease Control and Prevention (CDCP) in Atlanta and from Toronto, who have also isolated a novel coronavirus from patients with SARS.2,3 As other pathogens, such as human metapneumovirus and Chlamydia spp, are identified in SARS patients, it will be important to use control groups to determine their role in causality or as cofactors for severe disease.2,4 |
| doi_str_mv | 10.1016/S0140-6736(03)13084-X |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7124358</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S014067360313084X</els_id><sourcerecordid>328798731</sourcerecordid><originalsourceid>FETCH-LOGICAL-c570t-26535a169f0bba8769731cd1cdd8ca3fc272469566ded2d12d6f56f456061e333</originalsourceid><addsrcrecordid>eNqFkV1rFDEUhoMo7Vr7EyqDgujFaE4-Z24UKX4Uil7Ywt6FbHJGU2Yn22RmYP-9aXepVpBCIIE85805eQg5AfoWKKh3PygIWivN1WvK3wCnjaiXj8gChBa1FHr5mCzukEPyNOcrSqlQVB6QQ2AaoJwXRH-LM_aViykOdg5pypUdfJVxxoSVddOIVcK8CcmOMW2rvB18imt8Rp50ts94vN-PyOXnTxenX-vz71_OTj-e105qOtZMSS4tqLajq5VttGo1B-fL8o2zvHNMM6FaqZRHzzwwrzqpOiEVVYCc8yPyfpe7mVZr9A6HMdnebFJY27Q10QZz_2YIv8zPOBsNTHDZlIBX-4AUryfMo1mH7LDv7YBxykZzxrhkuoAv_wGv4pSGMpxhVLWtaEpThXrxPwralnIBjSiQ3EEuxZwTdnf9AjU39sytPXOjxlBubu2ZZal7_vewf6r2ugrwYQdg-fI5YDLZBRwc-pDQjcbH8MATvwFpNalU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>199034184</pqid></control><display><type>article</type><title>Novel coronavirus and severe acute respiratory syndrome</title><source>MEDLINE</source><source>Business Source Complete</source><source>ScienceDirect Journals (5 years ago - present)</source><source>ProQuest Central UK/Ireland</source><creator>Falsey, Ann R ; Walsh, Edward E</creator><creatorcontrib>Falsey, Ann R ; Walsh, Edward E</creatorcontrib><description>In today's Lancet, Joseph Peiris and colleagues provide strong evidence that SARS is associated with a novel coronavirus that has not been previously identified in human beings or animals, and begin the process of eliminating the many unknowns from this new syndrome (figure). The investigators used classic viral culture and serological techniques, as well as modern molecular genetic methods, to characterise and to determine the cause of the disease in 50 patients with SARS in Hong Kong. One of the strengths of their report, and an important means of establishing causality, is their analysis of specimens from control patients. None of 40 respiratory secretions from patients with other respiratory diseases contained coronavirus RNA, and none of 200 serum samples from blood donors had serum antibody to this new coronavirus. These findings significantly strengthen the tentative aetiological association reported by other investigators from the Centers for Disease Control and Prevention (CDCP) in Atlanta and from Toronto, who have also isolated a novel coronavirus from patients with SARS.2,3 As other pathogens, such as human metapneumovirus and Chlamydia spp, are identified in SARS patients, it will be important to use control groups to determine their role in causality or as cofactors for severe disease.2,4</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>DOI: 10.1016/S0140-6736(03)13084-X</identifier><identifier>PMID: 12711460</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Animals ; Causality ; Coronavirus - classification ; Coronavirus - isolation & purification ; Coronavirus Infections - epidemiology ; Coronavirus Infections - transmission ; Coronavirus Infections - virology ; Coronaviruses ; COVID-19 ; Diagnosis, Differential ; Disease Outbreaks ; Epidemics ; Epidemiology ; Hong Kong ; Humans ; Laboratories ; Legionnaire's disease ; Legionnaires' disease ; Medical research ; Respiratory diseases ; Severe acute respiratory syndrome ; Severe Acute Respiratory Syndrome - epidemiology ; Severe Acute Respiratory Syndrome - transmission ; Severe Acute Respiratory Syndrome - virology ; Sexually transmitted diseases ; STD ; Terrorism ; Viral infections ; Viruses ; World Health Organization</subject><ispartof>The Lancet (British edition), 2003-04, Vol.361 (9366), p.1312-1313</ispartof><rights>2003 Elsevier Ltd</rights><rights>Copyright Lancet Ltd. Apr 19, 2003</rights><rights>Copyright Elsevier Limited Apr 19, 2003</rights><rights>Copyright © 2003 Elsevier Ltd. All rights reserved. 2003 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c570t-26535a169f0bba8769731cd1cdd8ca3fc272469566ded2d12d6f56f456061e333</citedby><cites>FETCH-LOGICAL-c570t-26535a169f0bba8769731cd1cdd8ca3fc272469566ded2d12d6f56f456061e333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/199034184?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,3548,27923,27924,45994,64384,64386,64388,72240</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12711460$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Falsey, Ann R</creatorcontrib><creatorcontrib>Walsh, Edward E</creatorcontrib><title>Novel coronavirus and severe acute respiratory syndrome</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>In today's Lancet, Joseph Peiris and colleagues provide strong evidence that SARS is associated with a novel coronavirus that has not been previously identified in human beings or animals, and begin the process of eliminating the many unknowns from this new syndrome (figure). The investigators used classic viral culture and serological techniques, as well as modern molecular genetic methods, to characterise and to determine the cause of the disease in 50 patients with SARS in Hong Kong. One of the strengths of their report, and an important means of establishing causality, is their analysis of specimens from control patients. None of 40 respiratory secretions from patients with other respiratory diseases contained coronavirus RNA, and none of 200 serum samples from blood donors had serum antibody to this new coronavirus. These findings significantly strengthen the tentative aetiological association reported by other investigators from the Centers for Disease Control and Prevention (CDCP) in Atlanta and from Toronto, who have also isolated a novel coronavirus from patients with SARS.2,3 As other pathogens, such as human metapneumovirus and Chlamydia spp, are identified in SARS patients, it will be important to use control groups to determine their role in causality or as cofactors for severe disease.2,4</description><subject>Animals</subject><subject>Causality</subject><subject>Coronavirus - classification</subject><subject>Coronavirus - isolation & purification</subject><subject>Coronavirus Infections - epidemiology</subject><subject>Coronavirus Infections - transmission</subject><subject>Coronavirus Infections - virology</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Diagnosis, Differential</subject><subject>Disease Outbreaks</subject><subject>Epidemics</subject><subject>Epidemiology</subject><subject>Hong Kong</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Legionnaire's disease</subject><subject>Legionnaires' disease</subject><subject>Medical research</subject><subject>Respiratory diseases</subject><subject>Severe acute respiratory syndrome</subject><subject>Severe Acute Respiratory Syndrome - epidemiology</subject><subject>Severe Acute Respiratory Syndrome - transmission</subject><subject>Severe Acute Respiratory Syndrome - virology</subject><subject>Sexually transmitted diseases</subject><subject>STD</subject><subject>Terrorism</subject><subject>Viral infections</subject><subject>Viruses</subject><subject>World Health Organization</subject><issn>0140-6736</issn><issn>1474-547X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkV1rFDEUhoMo7Vr7EyqDgujFaE4-Z24UKX4Uil7Ywt6FbHJGU2Yn22RmYP-9aXepVpBCIIE85805eQg5AfoWKKh3PygIWivN1WvK3wCnjaiXj8gChBa1FHr5mCzukEPyNOcrSqlQVB6QQ2AaoJwXRH-LM_aViykOdg5pypUdfJVxxoSVddOIVcK8CcmOMW2rvB18imt8Rp50ts94vN-PyOXnTxenX-vz71_OTj-e105qOtZMSS4tqLajq5VttGo1B-fL8o2zvHNMM6FaqZRHzzwwrzqpOiEVVYCc8yPyfpe7mVZr9A6HMdnebFJY27Q10QZz_2YIv8zPOBsNTHDZlIBX-4AUryfMo1mH7LDv7YBxykZzxrhkuoAv_wGv4pSGMpxhVLWtaEpThXrxPwralnIBjSiQ3EEuxZwTdnf9AjU39sytPXOjxlBubu2ZZal7_vewf6r2ugrwYQdg-fI5YDLZBRwc-pDQjcbH8MATvwFpNalU</recordid><startdate>20030419</startdate><enddate>20030419</enddate><creator>Falsey, Ann R</creator><creator>Walsh, Edward E</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TT</scope><scope>0TZ</scope><scope>0U~</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8C2</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>KB~</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20030419</creationdate><title>Novel coronavirus and severe acute respiratory syndrome</title><author>Falsey, Ann R ; Walsh, Edward E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c570t-26535a169f0bba8769731cd1cdd8ca3fc272469566ded2d12d6f56f456061e333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Animals</topic><topic>Causality</topic><topic>Coronavirus - classification</topic><topic>Coronavirus - isolation & purification</topic><topic>Coronavirus Infections - epidemiology</topic><topic>Coronavirus Infections - transmission</topic><topic>Coronavirus Infections - virology</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Diagnosis, Differential</topic><topic>Disease Outbreaks</topic><topic>Epidemics</topic><topic>Epidemiology</topic><topic>Hong Kong</topic><topic>Humans</topic><topic>Laboratories</topic><topic>Legionnaire's disease</topic><topic>Legionnaires' disease</topic><topic>Medical research</topic><topic>Respiratory diseases</topic><topic>Severe acute respiratory syndrome</topic><topic>Severe Acute Respiratory Syndrome - epidemiology</topic><topic>Severe Acute Respiratory Syndrome - transmission</topic><topic>Severe Acute Respiratory Syndrome - virology</topic><topic>Sexually transmitted diseases</topic><topic>STD</topic><topic>Terrorism</topic><topic>Viral infections</topic><topic>Viruses</topic><topic>World Health Organization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Falsey, Ann R</creatorcontrib><creatorcontrib>Walsh, Edward E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>News PRO</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Global News & ABI/Inform Professional</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Lancet Titles</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>British Nursing Index</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Newsstand Professional</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Falsey, Ann R</au><au>Walsh, Edward E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel coronavirus and severe acute respiratory syndrome</atitle><jtitle>The Lancet (British edition)</jtitle><addtitle>Lancet</addtitle><date>2003-04-19</date><risdate>2003</risdate><volume>361</volume><issue>9366</issue><spage>1312</spage><epage>1313</epage><pages>1312-1313</pages><issn>0140-6736</issn><eissn>1474-547X</eissn><coden>LANCAO</coden><abstract>In today's Lancet, Joseph Peiris and colleagues provide strong evidence that SARS is associated with a novel coronavirus that has not been previously identified in human beings or animals, and begin the process of eliminating the many unknowns from this new syndrome (figure). The investigators used classic viral culture and serological techniques, as well as modern molecular genetic methods, to characterise and to determine the cause of the disease in 50 patients with SARS in Hong Kong. One of the strengths of their report, and an important means of establishing causality, is their analysis of specimens from control patients. None of 40 respiratory secretions from patients with other respiratory diseases contained coronavirus RNA, and none of 200 serum samples from blood donors had serum antibody to this new coronavirus. These findings significantly strengthen the tentative aetiological association reported by other investigators from the Centers for Disease Control and Prevention (CDCP) in Atlanta and from Toronto, who have also isolated a novel coronavirus from patients with SARS.2,3 As other pathogens, such as human metapneumovirus and Chlamydia spp, are identified in SARS patients, it will be important to use control groups to determine their role in causality or as cofactors for severe disease.2,4</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>12711460</pmid><doi>10.1016/S0140-6736(03)13084-X</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 2003-04, Vol.361 (9366), p.1312-1313 |
| issn | 0140-6736 1474-547X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7124358 |
| source | MEDLINE; Business Source Complete; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Animals Causality Coronavirus - classification Coronavirus - isolation & purification Coronavirus Infections - epidemiology Coronavirus Infections - transmission Coronavirus Infections - virology Coronaviruses COVID-19 Diagnosis, Differential Disease Outbreaks Epidemics Epidemiology Hong Kong Humans Laboratories Legionnaire's disease Legionnaires' disease Medical research Respiratory diseases Severe acute respiratory syndrome Severe Acute Respiratory Syndrome - epidemiology Severe Acute Respiratory Syndrome - transmission Severe Acute Respiratory Syndrome - virology Sexually transmitted diseases STD Terrorism Viral infections Viruses World Health Organization |
| title | Novel coronavirus and severe acute respiratory syndrome |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T17%3A50%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Novel%20coronavirus%20and%20severe%20acute%20respiratory%20syndrome&rft.jtitle=The%20Lancet%20(British%20edition)&rft.au=Falsey,%20Ann%20R&rft.date=2003-04-19&rft.volume=361&rft.issue=9366&rft.spage=1312&rft.epage=1313&rft.pages=1312-1313&rft.issn=0140-6736&rft.eissn=1474-547X&rft.coden=LANCAO&rft_id=info:doi/10.1016/S0140-6736(03)13084-X&rft_dat=%3Cproquest_pubme%3E328798731%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=199034184&rft_id=info:pmid/12711460&rft_els_id=S014067360313084X&rfr_iscdi=true |