Porcine deltacoronavirus induces apoptosis in swine testicular and LLC porcine kidney cell lines in vitro but not in infected intestinal enterocytes in vivo

•The mechanisms of PDCoV induced cell death in vivo and in vitro were unknown.•No PDCoV-infected enterocytes in vivo showed positive TUNEL staining.•TUNEL-positive signals (apoptotic nuclear fragmentation) were found in infected LLC-PK and ST cells that also showed cytopathic effects.•PDCoV does not...

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Veröffentlicht in:Veterinary microbiology 2016-01, Vol.182, p.57-63
Hauptverfasser: Jung, Kwonil, Hu, Hui, Saif, Linda J.
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Sprache:eng
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