Genome-wide methylation profiling in granulosa lutein cells of women with polycystic ovary syndrome (PCOS)

Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age, whose aetiology remains unclear. To improve our understanding of the molecular mechanisms underlying the disease, we conducted a genome-wide DNA methylation profiling in granulosa lutein cells c...

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Veröffentlicht in:	Molecular and cellular endocrinology 2020-01, Vol.500, p.110611-110611, Article 110611
Hauptverfasser:	Makrinou, E., Drong, A.W., Christopoulos, G., Lerner, A., Chapa-Chorda, I., Karaderi, T., Lavery, S., Hardy, K., Lindgren, C.M., Franks, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Case-Control Studies DNA Methylation DNA Mutational Analysis Epigenesis, Genetic EWAS Female Gene Regulatory Networks Humans Luteal Cells - chemistry Metabolic syndrome PCOS Polycystic Ovary Syndrome - genetics Reproduction Whole Genome Sequencing - methods
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