The bio in the ink: cartilage regeneration with bioprintable hydrogels and articular cartilage-derived progenitor cells

[Display omitted] Cell-laden hydrogels are the primary building blocks for bioprinting, and, also termed bioinks, are the foundations for creating structures that can potentially recapitulate the architecture of articular cartilage. To be functional, hydrogel constructs need to unlock the regenerati...

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Veröffentlicht in:	Acta biomaterialia 2017-10, Vol.61, p.41-53
Hauptverfasser:	Levato, Riccardo, Webb, William R., Otto, Iris A., Mensinga, Anneloes, Zhang, Yadan, van Rijen, Mattie, van Weeren, René, Khan, Ilyas M., Malda, Jos
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioengineering Biofabrication Biomarkers - metabolism Biomaterials Biomedical materials Bioprinting - methods Bone marrow Cartilage Cartilage (articular) Cartilage regeneration Cartilage, Articular - cytology Cell culture Cell Differentiation - drug effects Cell Differentiation - genetics Cells (biology) Cells, Cultured Chondrocytes Chondrogenesis - drug effects Chondrogenesis - genetics Chondroprogenitor cells Co-culture Coculture Techniques Collagen Compressive Strength DNA - metabolism Extracellular matrix Gelatin Gene expression Glycosaminoglycans Glycosaminoglycans - metabolism Horses Hydrogel Hydrogel, Polyethylene Glycol Dimethacrylate - pharmacology Hydrogels Hydrogels - pharmacology Hypertrophy Ink Lubrication Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - drug effects Mesenchymal Stem Cells - metabolism Mesenchyme Printing Regeneration (physiology) Regeneration - drug effects Regenerative medicine RNA, Messenger - genetics RNA, Messenger - metabolism Stem cells Stem Cells - cytology Stem Cells - drug effects Stromal cells Sus scrofa Three dimensional printing Tissue engineering
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