Immunotherapy against experimental canine visceral leishmaniasis with the saponin enriched-Leishmune® vaccine

Abstract In order to assess the immunotherapeutic potential on canine visceral leishmaniasis of the Leishmune® vaccine, formulated with an increased adjuvant concentration (1 mg of saponin rather than 0.5 mg), 24 mongrel dogs were infected with Leishmania (L.) chagasi . The enriched-Leishmune® vacci...

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Veröffentlicht in:	Vaccine 2007-08, Vol.25 (33), p.6176-6190
Hauptverfasser:	Santos, F.N, Borja-Cabrera, G.P, Miyashiro, L.M, Grechi, J, Reis, A.B, Moreira, M.A.B, Martins Filho, O.A, Luvizotto, M.C.R, Menz, I, Pessôa, L.M, Gonçalves, P.R, Palatnik, M, Palatnik-de-Sousa, C.B
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Applied microbiology Biological and medical sciences Canine visceral leishmaniasis DNA, Protozoan Dogs FML-vaccine Fundamental and applied biological sciences. Psychology Human protozoal diseases Hypersensitivity Immunization Immunoglobulin G - blood Immunotherapy Infectious diseases Kala-azar Leishmania Leishmania chagasi Leishmaniasis, Visceral - immunology Leishmaniasis, Visceral - therapy Leishmune ® vaccine Leshmaniasis Lymphocytes Medical sciences Microbiology Parasites Parasitic diseases Protozoal diseases Protozoan Vaccines - immunology QS21 Quillaja saponaria Molina Saponin Saponins - chemistry Time Factors Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Variance analysis Vector-borne diseases Zoonoses
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