Polygala fallax Hemsl combined with compound Sanqi granules relieves glomerulonephritis by regulating proliferation and apoptosis of glomerular mesangial cells

Objectives Glomerulonephritis is a serious kidney disease that can induce end-stage renal failure. The aberrant proliferation of mesangial cells is a cause of glomerulonephritis. Traditional Chinese medicines, such as Astragalus and Salvia miltrorrhiza, play important roles in the treatment of kidne...

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Veröffentlicht in:	Journal of international medical research 2020-01, Vol.48 (1), p.300060519894124-300060519894124
Hauptverfasser:	Chao, Shiwei, Xu, Qin, Dong, Shaoning, Guo, Min, Liu, Xusheng, Cheng, Xueren
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Cell growth Cell Line Cell Proliferation - drug effects Chinese medicine Drug Evaluation, Preclinical Drug Therapy, Combination - methods Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Glomerulonephritis - drug therapy Glomerulonephritis - immunology Glomerulonephritis - pathology Humans Kidney diseases Lipopolysaccharides - immunology Male Mesangial Cells - drug effects Mesangial Cells - immunology Mesangial Cells - pathology Mice Models, Animal Polygala - chemistry Validation Study
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