Accessory proteins of SARS-CoV and other coronaviruses

•The SARS-CoV genome encodes eight accessory proteins; none is essential for RNA replication.•Several appear to be involved in virus–host interactions and to influence the pathogenicity of the virus.•Some of these accessory proteins modulate the interferon pathway and the production of pro-inflammat...

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Veröffentlicht in:	Antiviral research 2014-09, Vol.109, p.97-109
Hauptverfasser:	Liu, Ding Xiang, Fung, To Sing, Chong, Kelvin Kian-Long, Shukla, Aditi, Hilgenfeld, Rolf
Format:	Artikel
Sprache:	eng
Schlagworte:	Accessory proteins Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Coronavirus - classification Coronavirus - genetics Coronavirus - metabolism Coronavirus Infections - virology Humans Medical sciences Open Reading Frames Other coronaviruses Pharmacology. Drug treatments Review SARS Virus - genetics SARS Virus - metabolism SARS-CoV Structure and function Viral Regulatory and Accessory Proteins - genetics Viral Regulatory and Accessory Proteins - metabolism
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