Hyper-phosphorylation of nsp2-related proteins of porcine reproductive and respiratory syndrome virus

Viruses exploit phosphorylation of both viral and host proteins to support viral replication. In this study, we demonstrate that porcine reproductive and respiratory syndrome virus replicase nsp2, and two nsp2-related −2/−1 frameshifting products, nsp2TF and nsp2N, are hyper-phosphorylated. By mappi...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2020-04, Vol.543, p.63-75
Hauptverfasser:	Shang, Pengcheng, Yuan, Fangfeng, Misra, Saurav, Li, Yanhua, Fang, Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	genomics Hyper-phosphorylation Intrinsically disordered protein nsp2-related proteins pathogenesis phosphorylation porcine reproductive and respiratory syndrome proteins PRRSV RNA Subgenomic RNA virus replication viruses
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