Assembly-free single-molecule sequencing recovers complete virus genomes from natural microbial communities

Viruses are the most abundant biological entities on Earth and play key roles in host ecology, evolution, and horizontal gene transfer. Despite recent progress in viral metagenomics, the inherent genetic complexity of virus populations still poses technical difficulties for recovering complete virus...

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Veröffentlicht in:	Genome research 2020-03, Vol.30 (3), p.437-446
Hauptverfasser:	Beaulaurier, John, Luo, Elaine, Eppley, John M, Uyl, Paul Den, Dai, Xiaoguang, Burger, Andrew, Turner, Daniel J, Pendelton, Matthew, Juul, Sissel, Harrington, Eoghan, DeLong, Edward F
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriophages - genetics Concatamers DNA Packaging Gene transfer Genome, Viral Genomes Horizontal transfer Metagenomics Method Nanopore Sequencing - methods Nucleotide sequence Packaging Phages Population genetics Seawater - virology Viruses
Online-Zugang:	Volltext
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