Infections in pediatric solid organ transplant recipients
Despite the progress made in graft and patient survival in recent years, infectious complications remain a major source of morbidity and mortality in pediatric solid organ transplant recipients. The risk of infection after transplant is determined by the interaction of several factors, including age...
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| Veröffentlicht in: | Seminars in pediatric surgery 2006-08, Vol.15 (3), p.153-161 |
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| creator | Fonseca-Aten, Monica Michaels, Marian G. |
| description | Despite the progress made in graft and patient survival in recent years, infectious complications remain a major source of morbidity and mortality in pediatric solid organ transplant recipients. The risk of infection after transplant is determined by the interaction of several factors, including age, type of organ transplanted, type and intensity of immunosuppression, environmental exposures, and the consequences of invasive procedures. Compared with adult transplant recipients, children are at higher risk of developing primary infection with various organisms after transplantation, as they often lack previous immunity from natural exposure to many microbes and often have not completed their primary immunization series at the time of transplantation. This article provides an overview of the risk factors, timing, and types of infectious complications associated with organ transplantation in children. |
| doi_str_mv | 10.1053/j.sempedsurg.2006.03.009 |
| format | Article |
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The risk of infection after transplant is determined by the interaction of several factors, including age, type of organ transplanted, type and intensity of immunosuppression, environmental exposures, and the consequences of invasive procedures. Compared with adult transplant recipients, children are at higher risk of developing primary infection with various organisms after transplantation, as they often lack previous immunity from natural exposure to many microbes and often have not completed their primary immunization series at the time of transplantation. 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This article provides an overview of the risk factors, timing, and types of infectious complications associated with organ transplantation in children.</description><subject>Age Factors</subject><subject>Bacterial Infections - etiology</subject><subject>Child</subject><subject>Environmental exposure</subject><subject>Humans</subject><subject>Infection in transplant recipients</subject><subject>Mycoses - etiology</subject><subject>Opportunistic infection</subject><subject>Opportunistic Infections - etiology</subject><subject>Organ Transplantation - adverse effects</subject><subject>Pediatric solid organ transplantation</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Virus Diseases - etiology</subject><issn>1055-8586</issn><issn>1532-9453</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PwyAYx4nRuDn9CqYnb60PUCi9mKjxZckSL3omlMJk6UqFzsRvL8sWpye5QPL8Xx5-CGUYCgyMXq-KaNaDaeMmLAsCwAugBUB9hKaYUZLXJaPH6Q2M5YIJPkFnMa4ACOeEnaIJ5gILTPkU1fPeGj0638fM9VnKdGoMTmfRd67NfFiqPhuD6uPQqX7MgtFucKYf4zk6saqL5mJ_z9Db48Pr_XO-eHma398uck1rUudNrQRrRVMRQVtVNmWpyorwypaWamyFqetKW2gFJdYCKVullRGMN0TzSmFFZ-hmlztsmrVpdeoOqpNDcGsVvqRXTv6d9O5dLv2nrHA6ACngah8Q_MfGxFGuXdSmS_8xfhMlFxwI4TgJxU6og48xGPtTgkFuucuVPHCXW-4SqEzck_Xy95IH4x50EtztBCah-nQmyKgTRp14J6SjbL37v-UbZvabuQ</recordid><startdate>200608</startdate><enddate>200608</enddate><creator>Fonseca-Aten, Monica</creator><creator>Michaels, Marian G.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200608</creationdate><title>Infections in pediatric solid organ transplant recipients</title><author>Fonseca-Aten, Monica ; Michaels, Marian G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3929-b9a85d8b7283da4b44a47267f4f3c1f8e997cf0d832ff024dacae856b2c67a1a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Age Factors</topic><topic>Bacterial Infections - etiology</topic><topic>Child</topic><topic>Environmental exposure</topic><topic>Humans</topic><topic>Infection in transplant recipients</topic><topic>Mycoses - etiology</topic><topic>Opportunistic infection</topic><topic>Opportunistic Infections - etiology</topic><topic>Organ Transplantation - adverse effects</topic><topic>Pediatric solid organ transplantation</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>Virus Diseases - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fonseca-Aten, Monica</creatorcontrib><creatorcontrib>Michaels, Marian G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Seminars in pediatric surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fonseca-Aten, Monica</au><au>Michaels, Marian G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Infections in pediatric solid organ transplant recipients</atitle><jtitle>Seminars in pediatric surgery</jtitle><addtitle>Semin Pediatr Surg</addtitle><date>2006-08</date><risdate>2006</risdate><volume>15</volume><issue>3</issue><spage>153</spage><epage>161</epage><pages>153-161</pages><issn>1055-8586</issn><eissn>1532-9453</eissn><abstract>Despite the progress made in graft and patient survival in recent years, infectious complications remain a major source of morbidity and mortality in pediatric solid organ transplant recipients. 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| fulltext | fulltext |
| identifier | ISSN: 1055-8586 |
| ispartof | Seminars in pediatric surgery, 2006-08, Vol.15 (3), p.153-161 |
| issn | 1055-8586 1532-9453 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7111100 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Age Factors Bacterial Infections - etiology Child Environmental exposure Humans Infection in transplant recipients Mycoses - etiology Opportunistic infection Opportunistic Infections - etiology Organ Transplantation - adverse effects Pediatric solid organ transplantation Risk Factors Time Factors Virus Diseases - etiology |
| title | Infections in pediatric solid organ transplant recipients |
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