The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry

Filoviruses such as Ebola virus and Marburg virus cause a severe haemorrhagic fever syndrome in humans for which there is no specific treatment. Since filoviruses use a complex route of cell entry that depends on numerous cellular factors, we hypothesized that there may be drugs already approved for...

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Veröffentlicht in:Journal of antimicrobial chemotherapy 2014-08, Vol.69 (8), p.2123-2131
Hauptverfasser: Gehring, Gerrit, Rohrmann, Katrin, Atenchong, Nkacheh, Mittler, Eva, Becker, Stephan, Dahlmann, Franziska, Pöhlmann, Stefan, Vondran, Florian W R, David, Sascha, Manns, Michael P, Ciesek, Sandra, von Hahn, Thomas
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Sprache:eng
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