Protective Effect of WC3 Vaccine Against Rotavirus Diarrhea in Infants During a Predominantly Serotype 1 Rotavirus Season

We used a double-blind, placebo-controlled trial to study the efficacy of WC3 rotavirus vaccine administered to 104 infants (ages, three to 12 months) before the rotavirus season. Forty-nine infants received vaccine; 55 received placebo. Rotavirus disease during this season was predominantly caused...

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Veröffentlicht in:	The Journal of infectious diseases 1988-09, Vol.158 (3), p.570-587
Hauptverfasser:	Clark, H Fred, Horian, Frances E., Bell, Louis M., Modesto, Karen, Gouvea, Vera, Plotkin, Stanley A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Viral - biosynthesis Antibody formation Biological and medical sciences Child, Preschool Diarrhea Diarrhea - prevention & control Double-Blind Method Feces - microbiology Female Gastroenteritis - prevention & control Human viral diseases Humans Infant Infants Infections Infectious diseases Male Medical sciences Original Original Articles Placebos Rotavirus Rotavirus - classification Rotavirus - immunology Rotavirus infections Rotavirus Infections - prevention & control Rotavirus Vaccines Seasons Vaccination Viral diseases Viral diseases of the digestive system Viral Vaccines Viruses
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