Protective Effect of a Mixture of Astragalus membranaceus and Lithospermum erythrorhizon Extract against Hepatic Steatosis in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mice

The present study aimed to evaluate the potential synergistic and protective effects of ALM16, a mixture of Astragalus membranaceus (AM) and Lithospermum erythrorhizon (LE) extract in a ratio of 7 : 3, against hepatic steatosis in high fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD)...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-11
Hauptverfasser:	Kim, Geum-Soog, Park, Yong Il, Lee, Young-Seob, Lee, Dae Young, Choi, Bo-Ram, Park, Gi Eun, Kim, Seong Cheol, Choi, Doo Jin, Park, Sung-Bum
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA carboxylase Alanine Alanine transaminase Alkaline phosphatase AMP AMP-activated protein kinase Aspartate aminotransferase Astragalus membranaceus Carnitine Carnitine palmitoyltransferase Cholesterol Diet Fatty acids Fatty liver Fatty-acid synthase Gene expression Herbs High density lipoprotein High fat diet Kinases L-Lactate dehydrogenase Laboratory animals Lactic acid Lipids Lithospermum erythrorhizon Liver diseases Low density lipoprotein Low density lipoproteins Metabolism Oral administration Palmitoyltransferase Phosphatases Protein binding Steatosis Sterol regulatory element-binding protein Synthesis Triglycerides Tumor necrosis factor-TNF γ-Glutamyltransferase
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