Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches

Genome-wide association studies (GWASs) have been widely applied to identify genetic factors that affect complex diseases or traits. Presently, the GWAS Catalog includes >2800 human studies. Of these, only a minority have investigated the susceptibility to infectious diseases or the response to t...

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Veröffentlicht in:	Infection, genetics and evolution genetics and evolution, 2018-12, Vol.66, p.286-307
Hauptverfasser:	Mozzi, Alessandra, Pontremoli, Chiara, Sironi, Manuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity - genetics Animals Biological Evolution Communicable Disease Control Communicable Diseases - etiology Communicable Diseases - therapy Genetic Association Studies Genetic Predisposition to Disease Genome-Wide Association Study GWAS Host-Pathogen Interactions - genetics Host-Pathogen Interactions - immunology Humans Immunity, Innate - genetics Infectious disease Phenotype Quantitative Trait Loci Quantitative Trait, Heritable Response to treatment or vaccine
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