Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice

Chronic alcohol abuse has a detrimental effect on the brain and liver. There is no effective treatment for these patients, and the mechanism underlying alcohol addiction and consequent alcohol-induced damage of the liver/brain axis remains unresolved. We compared experimental models of alcoholic liv...

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Veröffentlicht in:	JCI insight 2020-02, Vol.5 (3)
Hauptverfasser:	Xu, Jun, Ma, Hsiao-Yen, Liu, Xiao, Rosenthal, Sara, Baglieri, Jacopo, McCubbin, Ryan, Sun, Mengxi, Koyama, Yukinori, Geoffroy, Cedric G, Saijo, Kaoru, Shang, Linshan, Nishio, Takahiro, Maricic, Igor, Kreifeldt, Max, Kusumanchi, Praveen, Roberts, Amanda, Zheng, Binhai, Kumar, Vipin, Zengler, Karsten, Pizzo, Donald P, Hosseini, Mojgan, Contet, Candice, Glass, Christopher K, Liangpunsakul, Suthat, Tsukamoto, Hidekazu, Gao, Bin, Karin, Michael, Brenner, David A, Koob, George F, Kisseleva, Tatiana
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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