Studying immunity to zoonotic diseases in the natural host — keeping it real

Key Points Zoonotic viruses pose a serious threat to human and animal health. Studying the immune response to zoonotic pathogens in the natural reservoir hosts, rather than traditional animal models, offers important insights into control strategies. Comparative studies in natural host systems have...

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Veröffentlicht in:	Nature reviews. Immunology 2013-12, Vol.13 (12), p.851-861
Hauptverfasser:	Bean, Andrew G. D., Baker, Michelle L., Stewart, Cameron R., Cowled, Christopher, Deffrasnes, Celine, Wang, Lin-Fa, Lowenthal, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/181/2474 631/250/255 631/250/255/2514 Animals Biomedicine Care and treatment Disease Reservoirs - veterinary Disease Reservoirs - virology Domestic animals Host-parasite relationships Host-Pathogen Interactions Humans Immune response Immunology Infectious diseases Mammals Mice Middle East respiratory syndrome Models, Animal Pandemics Physiology, Comparative review-article Viruses Wildlife Zoonoses Zoonoses - immunology Zoonoses - transmission Zoonoses - virology
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