Scaling up single-cell mechanics to multicellular tissues - the role of the intermediate filament-desmosome network

Cells and tissues sense, respond to and translate mechanical forces into biochemical signals through mechanotransduction, which governs individual cell responses that drive gene expression, metabolic pathways and cell motility, and determines how cells work together in tissues. Mechanotransduction o...

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Veröffentlicht in:	Journal of cell science 2020-03, Vol.133 (6)
Hauptverfasser:	Broussard, Joshua A, Jaiganesh, Avinash, Zarkoob, Hoda, Conway, Daniel E, Dunn, Alexander R, Espinosa, Horacio D, Janmey, Paul A, Green, Kathleen J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adherens Junctions Cadherins Cell Adhesion Cytoskeleton Desmosomes Intermediate Filaments Mechanotransduction, Cellular Review
Online-Zugang:	Volltext
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