Plasma cortisol levels before and during low-dose hydrocortisone therapy and their relationship to hemodynamic improvement in patients with septic shock

To compare cortisol levels during "low-dose" hydrocortisone therapy to basal and ACTH-stimulated endogenous levels and to assess whether clinical course and the need for catecholamines depend on cortisol levels and/or pretreatment adrenocortical responsiveness. Prospective observational st...

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Veröffentlicht in:	Intensive care medicine 2000-12, Vol.26 (12), p.1747-1755
Hauptverfasser:	OPPERT, Michael, REINICKE, Albrecht, GRÄF, Klaus-Jürgen, BARCKOW, Detlef, FREI, Ulrich, ECKARDT, Kai-Uwe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone Adult Aged Aged, 80 and over Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - pharmacology Biological and medical sciences Cardiac Output - drug effects Catecholamines Drug Administration Schedule Drug dosages Drug Monitoring Drug Therapy, Combination Emergency and intensive care: infection, septic shock Female Hemodynamics Hemodynamics - drug effects Hormones Humans Hydrocortisone - administration & dosage Hydrocortisone - blood Hydrocortisone - pharmacology Infections Inflammation Infusions, Intravenous Intensive care Intensive care medicine Male Medical sciences Middle Aged Mortality Observational studies Original Plasma Prospective Studies Pulmonary arteries Sepsis Shock, Septic - drug therapy Shock, Septic - metabolism Shock, Septic - mortality Shock, Septic - physiopathology Steroids Treatment Outcome Vasoconstrictor Agents - therapeutic use
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