DNA-based bioanalytical microsystems for handheld device applications
This article reviews and highlights the current development of DNA-based bioanalytical microsystems for point-of-care diagnostics and on-site monitoring of food and water. Recent progresses in the miniaturization of various biological processing steps for the sample preparation, DNA amplification (p...
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| Veröffentlicht in: | Analytica chimica acta 2006-01, Vol.556 (1), p.26-37 |
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| container_title | Analytica chimica acta |
| container_volume | 556 |
| creator | Lee, Thomas Ming-Hung Hsing, I-Ming |
| description | This article reviews and highlights the current development of DNA-based bioanalytical microsystems for point-of-care diagnostics and on-site monitoring of food and water. Recent progresses in the miniaturization of various biological processing steps for the sample preparation, DNA amplification (polymerase chain reaction), and product detection are delineated in detail. Product detection approaches utilizing “portable” detection signals and electrochemistry-based methods are emphasized in this work. The strategies and challenges for the integration of individual processing module on the same chip are discussed. |
| doi_str_mv | 10.1016/j.aca.2005.05.075 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Analytica chimica acta, 2006-01, Vol.556 (1), p.26-37 |
| issn | 0003-2670 1873-4324 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7094345 |
| source | Elsevier ScienceDirect Journals |
| subjects | Bioanalytical microsystem DNA DNA amplification Electrochemical detection Lab-on-a-chip Review Sample preparation |
| title | DNA-based bioanalytical microsystems for handheld device applications |
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