Analysis of Time-Course, Dose-Effect, and Influencing Factors of Antidepressants in the Treatment of Acute Adult Patients With Major Depression

ObjectiveModel-based meta-analysis was used to describe the time-course and dose-effect relationships of antidepressants and also simultaneously investigate the impact of various factors on drug efficacy.MethodsThis study is a reanalysis of a published network meta-analysis. Only placebo-controlled...

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Veröffentlicht in:	The international journal of neuropsychopharmacology 2020-02, Vol.23 (2), p.76-87
Hauptverfasser:	Cheng, Qingqing, Huang, Jihan, Xu, Ling, Li, Yunfei, Li, Huafang, Shen, Yifeng, Zheng, Qingshan, Li, Lujin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Antidepressants Antidepressive Agents - administration & dosage Antidepressive Agents - pharmacokinetics Antidepressive Agents - pharmacology Depressive Disorder, Major - drug therapy Dosage and administration Dose-response relationship (Biochemistry) Dose-Response Relationship, Drug Female Humans Male Management Middle Aged Models, Statistical Network Meta-Analysis As Topic Outcome Assessment, Health Care - methods Outcome Assessment, Health Care - statistics & numerical data Pharmacology, Experimental Regular s Secondary data analysis
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