Anti-HMGCR Antibody-Positive Myopathy Shows Bcl-2-Positive Inflammation and Lymphocytic Accumulations

Abstract Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and antisignal recognition particle (SRP) antibodies are frequently associated with immune-mediated necrotizing myopathy (IMNM). However, the difference in clinical manifestations between anti-HMGCR and anti-SRP antibodies is uncl...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2020-04, Vol.79 (4), p.448-457
Hauptverfasser:	Kurashige, Takashi, Murao, Tomomi, Mine, Naoko, Sugiura, Tomohito, Inazuka, Yukiko, Kuraoka, Kazuya, Takahashi, Tetsuya, Maruyama, Hirofumi, Torii, Tsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Autoantibodies Diagnosis Genetic aspects Health aspects Lymphocytes Myositis Original Oxidoreductases Statins
Online-Zugang:	Volltext
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