RNAi, a new therapeutic strategy against viral infection

ABSTRACT RNA interference (RNAi) is an adaptive defense mechanism triggered by double-stranded RNA (dsRNA). It is a powerful reverse genetic tool that has been widely employed to silence gene expression in mammalian and human cells. RNAi-based gene therapies, especially in viral diseases have become...

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Veröffentlicht in:	Cell research 2004-12, Vol.14 (6), p.460-466
Hauptverfasser:	TAN, Fischer L, YIN, James Q
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Viral - drug effects Antigens, Viral - genetics Antiviral Agents - therapeutic use Biomedical and Life Sciences Cell Biology Humans Life Sciences Mammals review RNA Interference - physiology RNA, Small Interfering - therapeutic use Viral diseases Virus Diseases - drug therapy Virus Diseases - prevention & control Virus Diseases - virology
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