B cell lymphoproliferative disorders following hematopoietic stem cell transplantation : risk factors, treatment and outcome

Twenty-six cases of B cell lymphoproliferative disorder (BLPD) were identified among 2395 patients following hematopoietic stem cell transplants (HSCT) for which an overall incidence of BLPD was 1.2%. The true incidence was probably higher, since 9/26 of the diagnoses were made at autopsy. No BLPD w...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 1999-02, Vol.23 (3), p.251-258
Hauptverfasser:	GROSS, T. G, STEINBUCH, M, DEFOR, T, SHAPIRO, R. S, MCGLAVE, P, RAMSAY, N. K. C, WAGNER, J. E, FILIPOVICH, A. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyclovir - therapeutic use Adjuvants, Immunologic - therapeutic use Adolescent Adult Age AIDS/HIV Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens Antiviral Agents - therapeutic use Autografts Autopsies Autopsy B-Lymphocytes - virology Biological and medical sciences Blood Donors Bone marrow, stem cells transplantation. Graft versus host reaction Child Depletion Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - drug therapy Epstein-Barr Virus Infections - epidemiology Epstein-Barr Virus Infections - transmission Female Genetic Diseases, Inborn - therapy Graft vs Host Disease - etiology Graft vs Host Disease - mortality Graft-versus-host reaction Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic stem cells Herpesvirus 4, Human - isolation & purification Histocompatibility Histocompatibility antigen HLA Humans Immunocompromised Host Immunoglobulins, Intravenous - therapeutic use Immunophenotyping Immunoproliferative diseases Immunosuppression - adverse effects Incidence Infant Interferon Interferon-alpha - therapeutic use Leukemia - therapy Life Tables Lymphatic diseases Lymphocytes Lymphocytes T Lymphoproliferative Disorders - drug therapy Lymphoproliferative Disorders - epidemiology Lymphoproliferative Disorders - etiology Lymphoproliferative Disorders - immunology Lymphoproliferative Disorders - virology Male Medical sciences Middle Aged Multiple regression analysis Nuclear Family Parents Patients Remission Remission, Spontaneous Retrospective Studies Risk analysis Risk Factors Severe Combined Immunodeficiency - therapy Statistical analysis Stem cell transplantation Stem cells T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - pathology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous - adverse effects Transplants Transplants & implants Treatment Outcome
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