Effect of the deuterium on efficiency and type of adipogenic differentiation of human adipose-derived stem cells in vitro

In this study, we performed an adipogenic differentiation of human adipose-derived stem cells (ADSCs) in vitro with different deuterium content (natural, low and high) in the culture medium during differentiation process with parallel analysis of the gene expression, metabolic activity and cell viab...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.5217, Article 5217
Hauptverfasser:	Zlatska, Alona V., Vasyliev, Roman G., Gordiienko, Inna M., Rodnichenko, Anzhela E., Morozova, Maria A., Vulf, Maria A., Zubov, Dmytro O., Novikova, Svitlana N., Litvinova, Larisa S., Grebennikova, Tatiana V., Zlatskiy, Igor A., Syroeshkin, Anton V.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/532 631/61 631/61/2320 Adipocytes Adipocytes - cytology Adipocytes - drug effects Adipogenesis - drug effects Adipokines - biosynthesis Cell culture Cell differentiation Cell viability Cells, Cultured Chirality Chondrogenesis - drug effects Culture Media - pharmacology Cytotoxicity Deuterium Deuterium - pharmacology Diabetes mellitus Gene expression Gene Expression - drug effects Humanities and Social Sciences Humans Metabolic disorders Metabolic syndrome Metabolism Mitochondria multidisciplinary Osteogenesis - drug effects Science Science (multidisciplinary) Stem cells Stem Cells - cytology Stem Cells - drug effects Subcutaneous Fat - cytology Survival Uncoupling Protein 1 - biosynthesis Uncoupling Protein 1 - genetics
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