Synthesis, Biological Evaluation and Ligand Based Pharmacophore Modeling of New Aromatic Thiosemicarbazones as Potential Anticancer Agents

Two series of new aromatic thiosemicarbazone derivatives were synthesized by condensation of N -(4-cyanophenyl)hydrazine carbothioamide ( I ) and N -(4-methylsulfanylphenyl)hydrazine carbothioamide ( II ) with appropriate aromatic aldehydes in order to investigate their antiviral and cytostatic pote...

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Veröffentlicht in:	Pharmaceutical chemistry journal 2019-05, Vol.53 (2), p.139-149
Hauptverfasser:	Karaküçük-İyidoğan, A., Aydınöz, B., Taşkın-Tok, T., Oruç-Emre, E. E., Balzarini, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antiviral agents Bosutinib Cancer treatment Chemical plants Future predictions Influenza Influenza viruses Medicine Neratinib Organic Chemistry Pharmacology/Toxicology Pharmacy
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