The Molecular Control of Calcitonin Receptor Signaling

The calcitonin receptor (CTR) is a class B G protein-coupled receptor (GPCR) that responds to the peptide hormone calcitonin (CT). CTs are clinically approved for the treatment of bone diseases. We previously reported a 4.1 Å structure of the activated CTR bound to salmon CT (sCT) and heterotrimeric...

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Veröffentlicht in:	ACS pharmacology & translational science 2019-02, Vol.2 (1), p.31-51
Hauptverfasser:	dal Maso, Emma, Glukhova, Alisa, Zhu, Yue, Garcia-Nafria, Javier, Tate, Christopher G, Atanasio, Silvia, Reynolds, Christopher A, Ramírez-Aportela, Erney, Carazo, Jose-Maria, Hick, Caroline A, Furness, Sebastian G. B, Hay, Debbie L, Liang, Yi-Lynn, Miller, Laurence J, Christopoulos, Arthur, Wang, Ming-Wei, Wootten, Denise, Sexton, Patrick M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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