Inhibition of Staphylococcus aureus PriA Helicase by Flavonol Kaempferol

Staphylococcus aureus is an important etiological agent responsible for healthcare-associated infections. In this study, the effect of flavonoids on the inhibition of S. aureus PriA (SaPriA), an essential helicase for DNA replication restart, which is critical for bacterial survival, was investigate...

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Veröffentlicht in:	Protein Journal 2015-06, Vol.34 (3), p.169-172
Hauptverfasser:	Huang, Yen-Hua, Huang, Chien-Chih, Chen, Cheng-Chieh, Yang, Kai-Jr, Huang, Cheng-Yang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Animal Anatomy Bacterial Proteins - antagonists & inhibitors Bacterial Proteins - chemistry Bacterial Proteins - metabolism Biochemistry Bioorganic Chemistry Chemistry Chemistry and Materials Science Deoxyribonucleic acid DNA DNA Helicases - antagonists & inhibitors DNA Helicases - chemistry DNA Helicases - metabolism DNA replication Flavonoids Flavonoids - pharmacology Health aspects Histology Hydrolysis Isoflavones Kaempferols - pharmacology Morphology Organic Chemistry Staphylococcus aureus Staphylococcus aureus - enzymology Staphylococcus aureus infections Staphylococcus infections
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