Dysplastic Aberrant Crypt Foci: Biomarkers of Early Colorectal Neoplasia and Response to Preventive Intervention

The discovery of aberrant crypt foci (ACF) more than three decades ago not only enhanced our understanding of how colorectal tumors form, but provided new opportunities to detect lesions prior to adenoma development and intervene in the colorectal carcinogenesis process even earlier. Because not all...

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Veröffentlicht in:	Cancer prevention research (Philadelphia, Pa.) Pa.), 2020-03, Vol.13 (3), p.229-240
Hauptverfasser:	Clapper, Margie L, Chang, Wen-Chi L, Cooper, Harry S
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberrant Crypt Foci - diagnosis Aberrant Crypt Foci - genetics Aberrant Crypt Foci - pathology Aberrant Crypt Foci - therapy Adenoma - pathology Adenoma - prevention & control Adenomatous Polyposis Coli Protein - genetics Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Aspirin - pharmacology Aspirin - therapeutic use Atorvastatin - pharmacology Atorvastatin - therapeutic use Carcinogenesis - drug effects Catechin - administration & dosage Catechin - analogs & derivatives Clinical Trials as Topic Colon - diagnostic imaging Colon - drug effects Colon - pathology Colonoscopy Colorectal Neoplasms - pathology Colorectal Neoplasms - prevention & control Dietary Supplements Disease Models, Animal Humans Intestinal Mucosa - diagnostic imaging Intestinal Mucosa - drug effects Intestinal Mucosa - pathology Lycopene - administration & dosage Mice Mutation Treatment Outcome
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