Comprehensive analysis of somatic copy number alterations in clear cell renal cell carcinoma

Somatic copy number alterations (SCNAs) are important biological characteristics that can identify genome‐wide alterations in renal cell carcinoma (RCC). Recent studies have shown that SCNAs have potential value for determining the prognosis of RCC. We examined SCNAs using the Affymetrix platform to...

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Veröffentlicht in:	Molecular carcinogenesis 2020-04, Vol.59 (4), p.412-424
Hauptverfasser:	Tsuyukubo, Takashi, Ishida, Kazuyuki, Osakabe, Mitsumasa, Shiomi, Ei, Kato, Renpei, Takata, Ryo, Obara, Wataru, Sugai, Tamotsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - pathology clear cell renal cell carcinoma Clear cell-type renal cell carcinoma Cluster Analysis Cohort Studies Copy number DNA Copy Number Variations Female Genomes Heterozygosity Humans Kaplan-Meier Estimate Kidney cancer Kidney Neoplasms - genetics Kidney Neoplasms - pathology Loss of Heterozygosity Male Metastases Metastasis Middle Aged Multivariate Analysis Mutation patient prognosis Polymorphism, Single Nucleotide Prognosis renal carcinogenesis somatic copy number alteration Statistical analysis
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