Downregulation of SMOC2 expression in papillary thyroid carcinoma and its prognostic significance

Secreted Protein Acidic and Rich in Cysteine (SPARC)-related modular calcium-binding protein-2 (SMOC2), a secreted matricellular protein, is reported to be involved in various processes related to cancer progression such as regulating the cell cycle, angiogenesis, and invasion. However, its expressi...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.4853, Article 4853
Hauptverfasser:	Kim, Hye Sung, Choi, Jae Hyuck, Lee, Jae Young, Kang, JiHoon, Myung, Jae Kyung, Kim, Woo Ho, Jang, Bo Gun
Format:	Artikel
Sprache:	eng
Schlagworte:	13/105 13/106 14/63 42/109 631/67/1857 692/163/2743/1841 82/51 Amino Acid Substitution Angiogenesis Calcium-binding protein Calcium-Binding Proteins - genetics Calcium-Binding Proteins - metabolism Case-Control Studies Cell cycle Cell Line, Tumor CpG islands DNA Methylation Down-Regulation Epigenesis, Genetic Epithelial cells Female Gene expression Gene Expression Regulation, Neoplastic Humanities and Social Sciences Humans Hyperplasia Immunohistochemistry Lymph nodes Male Metastases multidisciplinary Neoplasm Staging Osteonectin Papillary thyroid carcinoma Prognosis Proteins Proto-Oncogene Proteins B-raf - genetics Science Science (multidisciplinary) Sex Characteristics Survival Analysis Thyroid Thyroid cancer Thyroid Cancer, Papillary - genetics Thyroid Cancer, Papillary - metabolism Thyroid Cancer, Papillary - pathology Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Thyroiditis Tumor Burden Tumor cell lines Tumors
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