The Surgical Benefit of Hysterolaparoscopy in Endometriosis-Related Infertility: A Single Centre Retrospective Study with a Minimum 2-Year Follow-Up
This study examined the fertility performance of women after combined hysterolaparoscopic surgical management of endometriosis. This study is a hospital-based retrospective review. Data collected from the records of all patients presented with endometriosis-related infertility using a checklist desi...
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| Veröffentlicht in: | Journal of clinical medicine 2020-02, Vol.9 (2), p.507 |
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| creator | Ekine, Atombosoba Adokiye Fülöp, István Tekse, István Rúcz, Árpád Jeges, Sara Koppán, Ágnes Koppán, Miklós |
| description | This study examined the fertility performance of women after combined hysterolaparoscopic surgical management of endometriosis.
This study is a hospital-based retrospective review.
Data collected from the records of all patients presented with endometriosis-related infertility using a checklist designed for the purpose.
A total of 81.3% (370/455) of women who have had the desire to have children became pregnant during the study period after the surgery. Of those who became pregnant, all three-hundred-forty-seven patients were followed to the end of their pregnancies. A successful live birth occurred in 94.2% (327/347) of individuals, and pregnancy loss occurred in 5.8% (20/347). The mean patient age was 34.1 ± 4.1 years, and the average duration of infertility was 3.4 ± 3.3 years. Pregnancy occurred spontaneously in 39.5% (146/370) of patients, after artificial insemination (AIH) in 3.8% (14/370) of women, and after in vitro fertilization-embryo transfer (IVF-ET) in 56.8% (210/370) of cases. Patients aged ≤ 35 years had a higher chance of conception post-surgery-84% versus 77%, respectively (
= 0.039). Based on the modes of pregnancy, the timely introduction of an assisted reproductive technique (ART) demonstrated a significant effect on fertility performance postsurgery. Comparatively, this effect was 91.3% vs. 74.1% among the ≤35- and >35-year-old age groups, respectively. There was no significant difference in reproductive performance based on stages of endometriosis, nor in the other parameters evaluated.
Our data are consistent with previous clinical studies regarding the management options of endometriosis-related infertility. Overall, the combined hysterolaparoscopy treatment is a very effective and reliable procedure, and is even more effective when combined with ART. It enhances women's wellbeing and quality of life, and significantly improves reproductive performance. |
| doi_str_mv | 10.3390/jcm9020507 |
| format | Article |
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This study is a hospital-based retrospective review.
Data collected from the records of all patients presented with endometriosis-related infertility using a checklist designed for the purpose.
A total of 81.3% (370/455) of women who have had the desire to have children became pregnant during the study period after the surgery. Of those who became pregnant, all three-hundred-forty-seven patients were followed to the end of their pregnancies. A successful live birth occurred in 94.2% (327/347) of individuals, and pregnancy loss occurred in 5.8% (20/347). The mean patient age was 34.1 ± 4.1 years, and the average duration of infertility was 3.4 ± 3.3 years. Pregnancy occurred spontaneously in 39.5% (146/370) of patients, after artificial insemination (AIH) in 3.8% (14/370) of women, and after in vitro fertilization-embryo transfer (IVF-ET) in 56.8% (210/370) of cases. Patients aged ≤ 35 years had a higher chance of conception post-surgery-84% versus 77%, respectively (
= 0.039). Based on the modes of pregnancy, the timely introduction of an assisted reproductive technique (ART) demonstrated a significant effect on fertility performance postsurgery. Comparatively, this effect was 91.3% vs. 74.1% among the ≤35- and >35-year-old age groups, respectively. There was no significant difference in reproductive performance based on stages of endometriosis, nor in the other parameters evaluated.
Our data are consistent with previous clinical studies regarding the management options of endometriosis-related infertility. Overall, the combined hysterolaparoscopy treatment is a very effective and reliable procedure, and is even more effective when combined with ART. It enhances women's wellbeing and quality of life, and significantly improves reproductive performance.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm9020507</identifier><identifier>PMID: 32069800</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Age groups ; Clinical medicine ; Cytokines ; Endometriosis ; Endometrium ; Endoscopy ; Fertility ; Gynecology ; Hospitals ; In vitro fertilization ; Infertility ; Laparoscopy ; Patients ; Pregnancy ; Quality of life ; Review ; Sperm ; Success ; Surgery ; Tumor necrosis factor-TNF ; Ultrasonic imaging ; Uterus ; Womens health</subject><ispartof>Journal of clinical medicine, 2020-02, Vol.9 (2), p.507</ispartof><rights>2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-50f9260e0ddc1f5a8d793682860daff7d7ad7d7df9ebf30510b4e5d02d7684803</citedby><cites>FETCH-LOGICAL-c406t-50f9260e0ddc1f5a8d793682860daff7d7ad7d7df9ebf30510b4e5d02d7684803</cites><orcidid>0000-0003-1834-9123</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073634/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073634/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32069800$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ekine, Atombosoba Adokiye</creatorcontrib><creatorcontrib>Fülöp, István</creatorcontrib><creatorcontrib>Tekse, István</creatorcontrib><creatorcontrib>Rúcz, Árpád</creatorcontrib><creatorcontrib>Jeges, Sara</creatorcontrib><creatorcontrib>Koppán, Ágnes</creatorcontrib><creatorcontrib>Koppán, Miklós</creatorcontrib><title>The Surgical Benefit of Hysterolaparoscopy in Endometriosis-Related Infertility: A Single Centre Retrospective Study with a Minimum 2-Year Follow-Up</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>This study examined the fertility performance of women after combined hysterolaparoscopic surgical management of endometriosis.
This study is a hospital-based retrospective review.
Data collected from the records of all patients presented with endometriosis-related infertility using a checklist designed for the purpose.
A total of 81.3% (370/455) of women who have had the desire to have children became pregnant during the study period after the surgery. Of those who became pregnant, all three-hundred-forty-seven patients were followed to the end of their pregnancies. A successful live birth occurred in 94.2% (327/347) of individuals, and pregnancy loss occurred in 5.8% (20/347). The mean patient age was 34.1 ± 4.1 years, and the average duration of infertility was 3.4 ± 3.3 years. Pregnancy occurred spontaneously in 39.5% (146/370) of patients, after artificial insemination (AIH) in 3.8% (14/370) of women, and after in vitro fertilization-embryo transfer (IVF-ET) in 56.8% (210/370) of cases. Patients aged ≤ 35 years had a higher chance of conception post-surgery-84% versus 77%, respectively (
= 0.039). Based on the modes of pregnancy, the timely introduction of an assisted reproductive technique (ART) demonstrated a significant effect on fertility performance postsurgery. Comparatively, this effect was 91.3% vs. 74.1% among the ≤35- and >35-year-old age groups, respectively. There was no significant difference in reproductive performance based on stages of endometriosis, nor in the other parameters evaluated.
Our data are consistent with previous clinical studies regarding the management options of endometriosis-related infertility. Overall, the combined hysterolaparoscopy treatment is a very effective and reliable procedure, and is even more effective when combined with ART. It enhances women's wellbeing and quality of life, and significantly improves reproductive performance.</description><subject>Age groups</subject><subject>Clinical medicine</subject><subject>Cytokines</subject><subject>Endometriosis</subject><subject>Endometrium</subject><subject>Endoscopy</subject><subject>Fertility</subject><subject>Gynecology</subject><subject>Hospitals</subject><subject>In vitro fertilization</subject><subject>Infertility</subject><subject>Laparoscopy</subject><subject>Patients</subject><subject>Pregnancy</subject><subject>Quality of life</subject><subject>Review</subject><subject>Sperm</subject><subject>Success</subject><subject>Surgery</subject><subject>Tumor necrosis factor-TNF</subject><subject>Ultrasonic imaging</subject><subject>Uterus</subject><subject>Womens health</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkd1qFTEUhQdRbKm98QEk4I0Io3uS-cl4IdRDawsVoT8XXoWcyc45OWSSMcm0zHv4wKa01moudgL7Y-2VvYridQUfGOvh424Ye6DQQPes2KfQdSUwzp4_ee8VhzHuIB_Oa1p1L4s9RqHtOcB-8etqi-RyDhszSEu-oENtEvGanC4xYfBWTjL4OPhpIcaRY6f8iCkYH00sL9DKhIqcOY0hGWvS8okckUvjNhbJCl0KSC4y7uOEQzI3eVSa1UJuTdoSSb4ZZ8Z5JLT8gTKQE2-tvy2vp1fFCy1txMOH-6C4Pjm-Wp2W59-_nq2OzsuhhjaVDeietoCg1FDpRnLV9azllLegpNad6qTKReke15pBU8G6xkYBVV3Law7soPh8rzvN6xHVcGdYWjEFM8qwCC-N-LfjzFZs_I3ooGMtq7PAuweB4H_OGJMYTRzQWunQz1FQ1vCG93ndGX37H7rzc3D5e4K2dQUNrYFl6v09NeSdxYD60UwF4i5v8TfvDL95av8R_ZMu-w02bKg1</recordid><startdate>20200213</startdate><enddate>20200213</enddate><creator>Ekine, Atombosoba Adokiye</creator><creator>Fülöp, István</creator><creator>Tekse, István</creator><creator>Rúcz, Árpád</creator><creator>Jeges, Sara</creator><creator>Koppán, Ágnes</creator><creator>Koppán, Miklós</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1834-9123</orcidid></search><sort><creationdate>20200213</creationdate><title>The Surgical Benefit of Hysterolaparoscopy in Endometriosis-Related Infertility: A Single Centre Retrospective Study with a Minimum 2-Year Follow-Up</title><author>Ekine, Atombosoba Adokiye ; Fülöp, István ; Tekse, István ; Rúcz, Árpád ; Jeges, Sara ; Koppán, Ágnes ; Koppán, Miklós</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-50f9260e0ddc1f5a8d793682860daff7d7ad7d7df9ebf30510b4e5d02d7684803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Age groups</topic><topic>Clinical medicine</topic><topic>Cytokines</topic><topic>Endometriosis</topic><topic>Endometrium</topic><topic>Endoscopy</topic><topic>Fertility</topic><topic>Gynecology</topic><topic>Hospitals</topic><topic>In vitro fertilization</topic><topic>Infertility</topic><topic>Laparoscopy</topic><topic>Patients</topic><topic>Pregnancy</topic><topic>Quality of life</topic><topic>Review</topic><topic>Sperm</topic><topic>Success</topic><topic>Surgery</topic><topic>Tumor necrosis factor-TNF</topic><topic>Ultrasonic imaging</topic><topic>Uterus</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ekine, Atombosoba Adokiye</creatorcontrib><creatorcontrib>Fülöp, István</creatorcontrib><creatorcontrib>Tekse, István</creatorcontrib><creatorcontrib>Rúcz, Árpád</creatorcontrib><creatorcontrib>Jeges, Sara</creatorcontrib><creatorcontrib>Koppán, Ágnes</creatorcontrib><creatorcontrib>Koppán, Miklós</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ekine, Atombosoba Adokiye</au><au>Fülöp, István</au><au>Tekse, István</au><au>Rúcz, Árpád</au><au>Jeges, Sara</au><au>Koppán, Ágnes</au><au>Koppán, Miklós</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Surgical Benefit of Hysterolaparoscopy in Endometriosis-Related Infertility: A Single Centre Retrospective Study with a Minimum 2-Year Follow-Up</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2020-02-13</date><risdate>2020</risdate><volume>9</volume><issue>2</issue><spage>507</spage><pages>507-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>This study examined the fertility performance of women after combined hysterolaparoscopic surgical management of endometriosis.
This study is a hospital-based retrospective review.
Data collected from the records of all patients presented with endometriosis-related infertility using a checklist designed for the purpose.
A total of 81.3% (370/455) of women who have had the desire to have children became pregnant during the study period after the surgery. Of those who became pregnant, all three-hundred-forty-seven patients were followed to the end of their pregnancies. A successful live birth occurred in 94.2% (327/347) of individuals, and pregnancy loss occurred in 5.8% (20/347). The mean patient age was 34.1 ± 4.1 years, and the average duration of infertility was 3.4 ± 3.3 years. Pregnancy occurred spontaneously in 39.5% (146/370) of patients, after artificial insemination (AIH) in 3.8% (14/370) of women, and after in vitro fertilization-embryo transfer (IVF-ET) in 56.8% (210/370) of cases. Patients aged ≤ 35 years had a higher chance of conception post-surgery-84% versus 77%, respectively (
= 0.039). Based on the modes of pregnancy, the timely introduction of an assisted reproductive technique (ART) demonstrated a significant effect on fertility performance postsurgery. Comparatively, this effect was 91.3% vs. 74.1% among the ≤35- and >35-year-old age groups, respectively. There was no significant difference in reproductive performance based on stages of endometriosis, nor in the other parameters evaluated.
Our data are consistent with previous clinical studies regarding the management options of endometriosis-related infertility. Overall, the combined hysterolaparoscopy treatment is a very effective and reliable procedure, and is even more effective when combined with ART. It enhances women's wellbeing and quality of life, and significantly improves reproductive performance.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>32069800</pmid><doi>10.3390/jcm9020507</doi><orcidid>https://orcid.org/0000-0003-1834-9123</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Age groups Clinical medicine Cytokines Endometriosis Endometrium Endoscopy Fertility Gynecology Hospitals In vitro fertilization Infertility Laparoscopy Patients Pregnancy Quality of life Review Sperm Success Surgery Tumor necrosis factor-TNF Ultrasonic imaging Uterus Womens health |
| title | The Surgical Benefit of Hysterolaparoscopy in Endometriosis-Related Infertility: A Single Centre Retrospective Study with a Minimum 2-Year Follow-Up |
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