Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use-A Randomised Trial in Older Malnourished People in Primary Care
Large trials assessing oral nutritional supplements (ONS) and dietary advice (DA) in primary care are lacking. This study examined effects of ONS + DA versus DA on intake, weight, QoL, healthcare use and satisfaction in malnourished free-living older people. Three hundred and eight people (71.5 ± 10...
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| description | Large trials assessing oral nutritional supplements (ONS) and dietary advice (DA) in primary care are lacking. This study examined effects of ONS + DA versus DA on intake, weight, QoL, healthcare use and satisfaction in malnourished free-living older people. Three hundred and eight people (71.5 ± 10.7y) were randomised to receive ONS + DA (n154) or DA (n154) for 12 weeks. At baseline, 4, 8, 12 weeks, intake, weight, QoL, healthcare use and satisfaction were measured. ONS + DA group (mean daily intake ONS 480 kcal; 21 g protein; 80% compliance) had significantly greater total energy and protein intakes (+401 kcal/d,
< 0.001; +15 g/d,
< 0.001) and weight gain (+0.8 kg;
< 0.001) compared to DA. QoL improved in both groups over time with a significant improvement in index with ONS + DA (
= 0.009). Significantly more participants found ONS + DA made a difference for them (
= 0.011), but no differences were found between groups using Euroqol. Compared to DA, healthcare use reduced with ONS + DA, (HCP visits by 34%, emergency admissions 50%, LOS 62%). Acceptability of both interventions was high (ONS 96%, DA 95%), with significantly more participants satisfied with ONS (89%) than DA (73%) (
= 0.009). This trial in primary care indicates that ONS are acceptable, make a difference to patients, significantly improve intake and weight, and reduce health care use with potential savings. |
| doi_str_mv | 10.3390/nu12020517 |
| format | Article |
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< 0.001; +15 g/d,
< 0.001) and weight gain (+0.8 kg;
< 0.001) compared to DA. QoL improved in both groups over time with a significant improvement in index with ONS + DA (
= 0.009). Significantly more participants found ONS + DA made a difference for them (
= 0.011), but no differences were found between groups using Euroqol. Compared to DA, healthcare use reduced with ONS + DA, (HCP visits by 34%, emergency admissions 50%, LOS 62%). Acceptability of both interventions was high (ONS 96%, DA 95%), with significantly more participants satisfied with ONS (89%) than DA (73%) (
= 0.009). This trial in primary care indicates that ONS are acceptable, make a difference to patients, significantly improve intake and weight, and reduce health care use with potential savings.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu12020517</identifier><identifier>PMID: 32085537</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Acceptability ; Aged ; Aged, 80 and over ; Body weight gain ; Cancer ; Clinical trials ; Cost control ; Counseling ; Dementia ; Diabetes ; Dietary minerals ; Dietary Proteins - administration & dosage ; Dietary Supplements ; Dietitians ; Dysphagia ; Eating ; Energy Intake ; Female ; Health care ; Humans ; Independent Living ; Lactose ; Lactose intolerance ; Male ; Malnutrition ; Malnutrition - etiology ; Malnutrition - psychology ; Malnutrition - therapy ; Middle Aged ; Nutrition research ; Nutrition Therapy - methods ; Older people ; Palliative care ; Participation ; Patient Acceptance of Health Care - statistics & numerical data ; Patient Satisfaction ; Primary care ; Primary Health Care ; Proteins ; Quality of Life ; Randomization ; Surgery ; Vitamins ; Weight reduction</subject><ispartof>Nutrients, 2020-02, Vol.12 (2), p.517</ispartof><rights>2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-228d845e19db74401b341706e17871edba7740913dba6d9df2a382d54f0d5f313</citedby><cites>FETCH-LOGICAL-c406t-228d845e19db74401b341706e17871edba7740913dba6d9df2a382d54f0d5f313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071441/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071441/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32085537$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smith, Trevor R</creatorcontrib><creatorcontrib>Cawood, Abbie L</creatorcontrib><creatorcontrib>Walters, Emily R</creatorcontrib><creatorcontrib>Guildford, Natasha</creatorcontrib><creatorcontrib>Stratton, Rebecca J</creatorcontrib><title>Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use-A Randomised Trial in Older Malnourished People in Primary Care</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>Large trials assessing oral nutritional supplements (ONS) and dietary advice (DA) in primary care are lacking. This study examined effects of ONS + DA versus DA on intake, weight, QoL, healthcare use and satisfaction in malnourished free-living older people. Three hundred and eight people (71.5 ± 10.7y) were randomised to receive ONS + DA (n154) or DA (n154) for 12 weeks. At baseline, 4, 8, 12 weeks, intake, weight, QoL, healthcare use and satisfaction were measured. ONS + DA group (mean daily intake ONS 480 kcal; 21 g protein; 80% compliance) had significantly greater total energy and protein intakes (+401 kcal/d,
< 0.001; +15 g/d,
< 0.001) and weight gain (+0.8 kg;
< 0.001) compared to DA. QoL improved in both groups over time with a significant improvement in index with ONS + DA (
= 0.009). Significantly more participants found ONS + DA made a difference for them (
= 0.011), but no differences were found between groups using Euroqol. Compared to DA, healthcare use reduced with ONS + DA, (HCP visits by 34%, emergency admissions 50%, LOS 62%). Acceptability of both interventions was high (ONS 96%, DA 95%), with significantly more participants satisfied with ONS (89%) than DA (73%) (
= 0.009). This trial in primary care indicates that ONS are acceptable, make a difference to patients, significantly improve intake and weight, and reduce health care use with potential savings.</description><subject>Acceptability</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body weight gain</subject><subject>Cancer</subject><subject>Clinical trials</subject><subject>Cost control</subject><subject>Counseling</subject><subject>Dementia</subject><subject>Diabetes</subject><subject>Dietary minerals</subject><subject>Dietary Proteins - administration & dosage</subject><subject>Dietary Supplements</subject><subject>Dietitians</subject><subject>Dysphagia</subject><subject>Eating</subject><subject>Energy Intake</subject><subject>Female</subject><subject>Health care</subject><subject>Humans</subject><subject>Independent Living</subject><subject>Lactose</subject><subject>Lactose intolerance</subject><subject>Male</subject><subject>Malnutrition</subject><subject>Malnutrition - etiology</subject><subject>Malnutrition - psychology</subject><subject>Malnutrition - therapy</subject><subject>Middle Aged</subject><subject>Nutrition research</subject><subject>Nutrition Therapy - methods</subject><subject>Older people</subject><subject>Palliative care</subject><subject>Participation</subject><subject>Patient Acceptance of Health Care - statistics & numerical data</subject><subject>Patient Satisfaction</subject><subject>Primary care</subject><subject>Primary Health Care</subject><subject>Proteins</subject><subject>Quality of Life</subject><subject>Randomization</subject><subject>Surgery</subject><subject>Vitamins</subject><subject>Weight reduction</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkd9KHDEUxkOxVLHe9AFKwBspjM2_SWZuCrK0KmhXtnodspMzbmRmMk0mgk_TVzXjWqvNTQ58v3w55zsIfaLkmPOafB0SZYSRkqp3aI8RxQopBd95Ve-igxjvyHwUUZJ_QLuckaosudpDf1Zg7ENxaSzgZTAd_pmm4Cbnh1z_SuPYQQ_DFPF5PwZ_D2_0ZZoa30PEZrB4BTY1gM_AdNMGL0wAfBOhOMGrrPreRbD4Orj8zA142VkI-NJ0g0_BxU3WrsDnz2bxKrjehIcnj4_ofWu6CAfP9z66-fH9enFWXCxPzxcnF0UjiJwKxipbiRJobddKCELXXFBFJFBVKQp2bZQSpKY8V9LWtmWGV8yWoiW2bDnl--jb1ndM6x5sk2fOaehx24r2xum3yuA2-tbf6xwpFWI2OHo2CP53gjjpPHIDXWcG8ClqxmUOndZVmdHD_9C7nEIOdKbqkjBJqMzUly3VBB9jgPalGUr0vHr9b_UZ_vy6_Rf076L5IzzEqpM</recordid><startdate>20200218</startdate><enddate>20200218</enddate><creator>Smith, Trevor R</creator><creator>Cawood, Abbie L</creator><creator>Walters, Emily R</creator><creator>Guildford, Natasha</creator><creator>Stratton, Rebecca J</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200218</creationdate><title>Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use-A Randomised Trial in Older Malnourished People in Primary Care</title><author>Smith, Trevor R ; Cawood, Abbie L ; Walters, Emily R ; Guildford, Natasha ; Stratton, Rebecca J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-228d845e19db74401b341706e17871edba7740913dba6d9df2a382d54f0d5f313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acceptability</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body weight gain</topic><topic>Cancer</topic><topic>Clinical trials</topic><topic>Cost control</topic><topic>Counseling</topic><topic>Dementia</topic><topic>Diabetes</topic><topic>Dietary minerals</topic><topic>Dietary Proteins - administration & dosage</topic><topic>Dietary Supplements</topic><topic>Dietitians</topic><topic>Dysphagia</topic><topic>Eating</topic><topic>Energy Intake</topic><topic>Female</topic><topic>Health care</topic><topic>Humans</topic><topic>Independent Living</topic><topic>Lactose</topic><topic>Lactose intolerance</topic><topic>Male</topic><topic>Malnutrition</topic><topic>Malnutrition - etiology</topic><topic>Malnutrition - psychology</topic><topic>Malnutrition - therapy</topic><topic>Middle Aged</topic><topic>Nutrition research</topic><topic>Nutrition Therapy - methods</topic><topic>Older people</topic><topic>Palliative care</topic><topic>Participation</topic><topic>Patient Acceptance of Health Care - statistics & numerical data</topic><topic>Patient Satisfaction</topic><topic>Primary care</topic><topic>Primary Health Care</topic><topic>Proteins</topic><topic>Quality of Life</topic><topic>Randomization</topic><topic>Surgery</topic><topic>Vitamins</topic><topic>Weight reduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smith, Trevor R</creatorcontrib><creatorcontrib>Cawood, Abbie L</creatorcontrib><creatorcontrib>Walters, Emily R</creatorcontrib><creatorcontrib>Guildford, Natasha</creatorcontrib><creatorcontrib>Stratton, Rebecca J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Smith, Trevor R</au><au>Cawood, Abbie L</au><au>Walters, Emily R</au><au>Guildford, Natasha</au><au>Stratton, Rebecca J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use-A Randomised Trial in Older Malnourished People in Primary Care</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2020-02-18</date><risdate>2020</risdate><volume>12</volume><issue>2</issue><spage>517</spage><pages>517-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>Large trials assessing oral nutritional supplements (ONS) and dietary advice (DA) in primary care are lacking. This study examined effects of ONS + DA versus DA on intake, weight, QoL, healthcare use and satisfaction in malnourished free-living older people. Three hundred and eight people (71.5 ± 10.7y) were randomised to receive ONS + DA (n154) or DA (n154) for 12 weeks. At baseline, 4, 8, 12 weeks, intake, weight, QoL, healthcare use and satisfaction were measured. ONS + DA group (mean daily intake ONS 480 kcal; 21 g protein; 80% compliance) had significantly greater total energy and protein intakes (+401 kcal/d,
< 0.001; +15 g/d,
< 0.001) and weight gain (+0.8 kg;
< 0.001) compared to DA. QoL improved in both groups over time with a significant improvement in index with ONS + DA (
= 0.009). Significantly more participants found ONS + DA made a difference for them (
= 0.011), but no differences were found between groups using Euroqol. Compared to DA, healthcare use reduced with ONS + DA, (HCP visits by 34%, emergency admissions 50%, LOS 62%). Acceptability of both interventions was high (ONS 96%, DA 95%), with significantly more participants satisfied with ONS (89%) than DA (73%) (
= 0.009). This trial in primary care indicates that ONS are acceptable, make a difference to patients, significantly improve intake and weight, and reduce health care use with potential savings.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>32085537</pmid><doi>10.3390/nu12020517</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Nutrients, 2020-02, Vol.12 (2), p.517 |
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| subjects | Acceptability Aged Aged, 80 and over Body weight gain Cancer Clinical trials Cost control Counseling Dementia Diabetes Dietary minerals Dietary Proteins - administration & dosage Dietary Supplements Dietitians Dysphagia Eating Energy Intake Female Health care Humans Independent Living Lactose Lactose intolerance Male Malnutrition Malnutrition - etiology Malnutrition - psychology Malnutrition - therapy Middle Aged Nutrition research Nutrition Therapy - methods Older people Palliative care Participation Patient Acceptance of Health Care - statistics & numerical data Patient Satisfaction Primary care Primary Health Care Proteins Quality of Life Randomization Surgery Vitamins Weight reduction |
| title | Ready-Made Oral Nutritional Supplements Improve Nutritional Outcomes and Reduce Health Care Use-A Randomised Trial in Older Malnourished People in Primary Care |
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