Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes
This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the reduction of at least 5% of body weight compared to baseline and (2) the percentage of participants in which fasting blood glucose (FBG) normali...
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| Veröffentlicht in: | Nutrients 2020-02, Vol.12 (2), p.464 |
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| creator | Wani, Kaiser Alfawaz, Hanan Alnaami, Abdullah M Sabico, Shaun Khattak, Malak Nawaz Khan Al-Attas, Omar Alokail, Majed S Alharbi, Mohammed Chrousos, George Kumar, Sudhesh Al-Daghri, Nasser M |
| description | This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the reduction of at least 5% of body weight compared to baseline and (2) the percentage of participants in which fasting blood glucose (FBG) normalizes ( |
| doi_str_mv | 10.3390/nu12020464 |
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= 21) of the subjects in the IG arm discontinued, compared to 8% (
= 12) in the GA arm. Data from completers (92% (
= 138) and 86% (
= 129) participants in GA and IG arms, respectively) were considered for the final analysis. Post-intervention, 37.2% (
= 48) of participants in the IG group had ≥5% weight reduction, as compared to 12.3% (
= 17) in the GA group (
< 0.01). Similarly, the percentage of participants who normalized their FBG post-intervention was 46.5% (
= 60) in the IG group compared to 21.7% (
= 30) in the GA group (
< 0.01). A 12-month Diabetes Prevention Program (DPP)-styled intensive lifestyle program translated effectively in decreasing weight and improving fasting glucose compared to the GA group in predominantly overweight/obese Saudi adults with prediabetes, suggesting that in the case of guided intervention programs, people are willing to participate and possibly change a sedentary lifestyle.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu12020464</identifier><identifier>PMID: 32059477</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adult ; Adults ; Aged ; Anthropometry ; Arabs ; Blood Glucose ; Blood pressure ; Body Weight ; Body weight loss ; Cholesterol ; Collaboration ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - prevention & control ; Diet, Reducing ; Disease control ; Exercise ; Expatriates ; Fasting ; Fasting - blood ; Female ; Glucose ; Healthy Lifestyle ; Humans ; Immunoglobulins ; Insulin ; Intervention ; Laboratory testing ; Lifestyles ; Male ; Middle Aged ; Monitoring, Physiologic - methods ; Obesity ; Overweight ; Patient Participation ; Physical activity ; Prediabetic State - diagnosis ; Prevention ; Primary care ; Time Factors ; Weight control ; Weight Loss ; Weight reduction ; Womens health</subject><ispartof>Nutrients, 2020-02, Vol.12 (2), p.464</ispartof><rights>2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-b3fff0b3cd21038773415093daa49012047a827d5498370a8ab87d8a2658884d3</citedby><cites>FETCH-LOGICAL-c406t-b3fff0b3cd21038773415093daa49012047a827d5498370a8ab87d8a2658884d3</cites><orcidid>0000-0001-9568-6516 ; 0000-0002-5248-2350 ; 0000-0002-1493-7297 ; 0000-0001-5472-1725</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071332/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071332/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32059477$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wani, Kaiser</creatorcontrib><creatorcontrib>Alfawaz, Hanan</creatorcontrib><creatorcontrib>Alnaami, Abdullah M</creatorcontrib><creatorcontrib>Sabico, Shaun</creatorcontrib><creatorcontrib>Khattak, Malak Nawaz Khan</creatorcontrib><creatorcontrib>Al-Attas, Omar</creatorcontrib><creatorcontrib>Alokail, Majed S</creatorcontrib><creatorcontrib>Alharbi, Mohammed</creatorcontrib><creatorcontrib>Chrousos, George</creatorcontrib><creatorcontrib>Kumar, Sudhesh</creatorcontrib><creatorcontrib>Al-Daghri, Nasser M</creatorcontrib><title>Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the reduction of at least 5% of body weight compared to baseline and (2) the percentage of participants in which fasting blood glucose (FBG) normalizes (<5.6 mmol/L) post-intervention, in predominantly overweight/obese Saudi adults with impaired fasting glucose. A total of 300 Saudi adults with prediabetes at baseline (FBG 5.6-6.9 mmol/L) were enrolled to receive either general advice (GA) or a rigorous, self-monitored, lifestyle modification program (intervention group, IG) for 12 months, focused on food choices, physical activity, and weight loss. Anthropometric and biochemical estimations were analyzed at baseline, 6, and 12 months. At baseline, 136/150 in the GA group (90.7%) and 127/150 in the IG group (84.7%) were either overweight or obese. A total of 14% (
= 21) of the subjects in the IG arm discontinued, compared to 8% (
= 12) in the GA arm. Data from completers (92% (
= 138) and 86% (
= 129) participants in GA and IG arms, respectively) were considered for the final analysis. Post-intervention, 37.2% (
= 48) of participants in the IG group had ≥5% weight reduction, as compared to 12.3% (
= 17) in the GA group (
< 0.01). Similarly, the percentage of participants who normalized their FBG post-intervention was 46.5% (
= 60) in the IG group compared to 21.7% (
= 30) in the GA group (
< 0.01). A 12-month Diabetes Prevention Program (DPP)-styled intensive lifestyle program translated effectively in decreasing weight and improving fasting glucose compared to the GA group in predominantly overweight/obese Saudi adults with prediabetes, suggesting that in the case of guided intervention programs, people are willing to participate and possibly change a sedentary lifestyle.</description><subject>Adult</subject><subject>Adults</subject><subject>Aged</subject><subject>Anthropometry</subject><subject>Arabs</subject><subject>Blood Glucose</subject><subject>Blood pressure</subject><subject>Body Weight</subject><subject>Body weight loss</subject><subject>Cholesterol</subject><subject>Collaboration</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - diagnosis</subject><subject>Diabetes Mellitus, Type 2 - prevention & control</subject><subject>Diet, Reducing</subject><subject>Disease control</subject><subject>Exercise</subject><subject>Expatriates</subject><subject>Fasting</subject><subject>Fasting - blood</subject><subject>Female</subject><subject>Glucose</subject><subject>Healthy Lifestyle</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Insulin</subject><subject>Intervention</subject><subject>Laboratory testing</subject><subject>Lifestyles</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Monitoring, Physiologic - methods</subject><subject>Obesity</subject><subject>Overweight</subject><subject>Patient Participation</subject><subject>Physical activity</subject><subject>Prediabetic State - diagnosis</subject><subject>Prevention</subject><subject>Primary care</subject><subject>Time Factors</subject><subject>Weight control</subject><subject>Weight Loss</subject><subject>Weight reduction</subject><subject>Womens health</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkU1r3DAQhkVpaMI2l_6AIuilFNzI-rDkS2EJ-YItm0N7FrI92lWwpVSSNyz989GSNE2rywzMw6t35kXoQ02-MtaSMz_XlFDCG_4GnVAiadU0nL191R-j05TuyOFJIhv2Dh0zSkTLpTxBvy-shT4nHCxe4ppW34PPW3zjM_jkdoBXzkLK-xFwmbgcovMbfBvDJpoJO19aGMLkvPF53OP1DuIDuM02n607SICX0XR4Ocxj-eLBFeUD70wHGdJ7dGTNmOD0uS7Qz8uLH-fX1Wp9dXO-XFU9J02uOmatJR3rB1oTpqRkvBakZYMxvCVley6NonIQvFVMEqNMp-SgDG2EUooPbIG-Penez90EQw8-RzPq--gmE_c6GKf_nXi31Zuw0-VcNWO0CHx-Fojh11zOoSeXehhH4yHMSVMmRNsIWkwt0Kf_0LswR1_WK1QrCFVM8EJ9eaL6GFKKYF_M1EQfYtV_Yy3wx9f2X9A_IbJHpsqdGQ</recordid><startdate>20200212</startdate><enddate>20200212</enddate><creator>Wani, Kaiser</creator><creator>Alfawaz, Hanan</creator><creator>Alnaami, Abdullah M</creator><creator>Sabico, Shaun</creator><creator>Khattak, Malak Nawaz Khan</creator><creator>Al-Attas, Omar</creator><creator>Alokail, Majed S</creator><creator>Alharbi, Mohammed</creator><creator>Chrousos, George</creator><creator>Kumar, Sudhesh</creator><creator>Al-Daghri, Nasser M</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9568-6516</orcidid><orcidid>https://orcid.org/0000-0002-5248-2350</orcidid><orcidid>https://orcid.org/0000-0002-1493-7297</orcidid><orcidid>https://orcid.org/0000-0001-5472-1725</orcidid></search><sort><creationdate>20200212</creationdate><title>Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes</title><author>Wani, Kaiser ; Alfawaz, Hanan ; Alnaami, Abdullah M ; Sabico, Shaun ; Khattak, Malak Nawaz Khan ; Al-Attas, Omar ; Alokail, Majed S ; Alharbi, Mohammed ; Chrousos, George ; Kumar, Sudhesh ; Al-Daghri, Nasser M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-b3fff0b3cd21038773415093daa49012047a827d5498370a8ab87d8a2658884d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Adults</topic><topic>Aged</topic><topic>Anthropometry</topic><topic>Arabs</topic><topic>Blood Glucose</topic><topic>Blood pressure</topic><topic>Body Weight</topic><topic>Body weight loss</topic><topic>Cholesterol</topic><topic>Collaboration</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Type 2 - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wani, Kaiser</au><au>Alfawaz, Hanan</au><au>Alnaami, Abdullah M</au><au>Sabico, Shaun</au><au>Khattak, Malak Nawaz Khan</au><au>Al-Attas, Omar</au><au>Alokail, Majed S</au><au>Alharbi, Mohammed</au><au>Chrousos, George</au><au>Kumar, Sudhesh</au><au>Al-Daghri, Nasser M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2020-02-12</date><risdate>2020</risdate><volume>12</volume><issue>2</issue><spage>464</spage><pages>464-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>This 12-month, randomized, controlled lifestyle intervention study was aimed at assessing the effectiveness of a lifestyle intervention in terms of (1) the reduction of at least 5% of body weight compared to baseline and (2) the percentage of participants in which fasting blood glucose (FBG) normalizes (<5.6 mmol/L) post-intervention, in predominantly overweight/obese Saudi adults with impaired fasting glucose. A total of 300 Saudi adults with prediabetes at baseline (FBG 5.6-6.9 mmol/L) were enrolled to receive either general advice (GA) or a rigorous, self-monitored, lifestyle modification program (intervention group, IG) for 12 months, focused on food choices, physical activity, and weight loss. Anthropometric and biochemical estimations were analyzed at baseline, 6, and 12 months. At baseline, 136/150 in the GA group (90.7%) and 127/150 in the IG group (84.7%) were either overweight or obese. A total of 14% (
= 21) of the subjects in the IG arm discontinued, compared to 8% (
= 12) in the GA arm. Data from completers (92% (
= 138) and 86% (
= 129) participants in GA and IG arms, respectively) were considered for the final analysis. Post-intervention, 37.2% (
= 48) of participants in the IG group had ≥5% weight reduction, as compared to 12.3% (
= 17) in the GA group (
< 0.01). Similarly, the percentage of participants who normalized their FBG post-intervention was 46.5% (
= 60) in the IG group compared to 21.7% (
= 30) in the GA group (
< 0.01). A 12-month Diabetes Prevention Program (DPP)-styled intensive lifestyle program translated effectively in decreasing weight and improving fasting glucose compared to the GA group in predominantly overweight/obese Saudi adults with prediabetes, suggesting that in the case of guided intervention programs, people are willing to participate and possibly change a sedentary lifestyle.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>32059477</pmid><doi>10.3390/nu12020464</doi><orcidid>https://orcid.org/0000-0001-9568-6516</orcidid><orcidid>https://orcid.org/0000-0002-5248-2350</orcidid><orcidid>https://orcid.org/0000-0002-1493-7297</orcidid><orcidid>https://orcid.org/0000-0001-5472-1725</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Nutrients, 2020-02, Vol.12 (2), p.464 |
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| source | MDPI - Multidisciplinary Digital Publishing Institute; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Adult Adults Aged Anthropometry Arabs Blood Glucose Blood pressure Body Weight Body weight loss Cholesterol Collaboration Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - prevention & control Diet, Reducing Disease control Exercise Expatriates Fasting Fasting - blood Female Glucose Healthy Lifestyle Humans Immunoglobulins Insulin Intervention Laboratory testing Lifestyles Male Middle Aged Monitoring, Physiologic - methods Obesity Overweight Patient Participation Physical activity Prediabetic State - diagnosis Prevention Primary care Time Factors Weight control Weight Loss Weight reduction Womens health |
| title | Effects of A 12-Month Intensive Lifestyle Monitoring Program in Predominantly Overweight/Obese Arab Adults with Prediabetes |
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