Lactate-Fortified Puerariae Radix Fermented by Bifidobacterium breve Improved Diet-Induced Metabolic Dysregulation via Alteration of Gut Microbial Communities

(PR), the dried root of , is reported to possess therapeutic efficacies against various diseases including obesity, diabetes, and hypertension. Fermentation-driven bioactivation of herbal medicines can result in improved therapeutic potencies and efficacies. C57BL/6J mice were fed a high-fat diet an...

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Veröffentlicht in:	Nutrients 2020-01, Vol.12 (2), p.276
Hauptverfasser:	Choi, Yura, Bose, Shambhunath, Shin, Na Rae, Song, Eun-Ji, Nam, Young-Do, Kim, Hojun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Animals Bifidobacterium breve Blood Glucose - drug effects Body weight Body weight gain Diabetes Diabetes mellitus Diet Diet, High-Fat Energy metabolism Fat metabolism Females Fermentation Fructose Gene expression Glucose Glucose metabolism Glucose tolerance Herbal medicine High fat diet Homeostasis Hypertension Inflammation Insulin resistance Interleukin 6 Intestinal microflora Intestine Kinases Laboratory animals Lactates - pharmacology Lactic acid Lipid metabolism Lipid Metabolism - drug effects Lipids Lipoproteins Liver Metabolic Diseases - drug therapy Metabolic Diseases - etiology Metabolic Diseases - microbiology Metabolic disorders Mice Mice, Inbred C57BL Microbial activity Microbiomes Microbiota Microbiota - drug effects Microorganisms Monocyte chemoattractant protein 1 Obesity Phosphorylation Plant Extracts - pharmacology Plant Roots Probiotics Protective Agents - pharmacology Pueraria rRNA 16S Tumor necrosis factor-α Weight control
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