Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma

Background Ubiquitin-specific protease 22 (USP22) is described as a key subunit of the Spt-Ada-Gcn5 acetyl transferase complex, which plays an important role in the prognosis and resistance to chemotherapy drugs in hepatocellular carcinoma (HCC). Silent information regulator 1 (SIRT1) is a member of...

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Veröffentlicht in:	Digestive diseases and sciences 2020-04, Vol.65 (4), p.1064-1073
Hauptverfasser:	Wen, Xue, Ling, Sunbin, Wu, Weiqiang, Shan, Qiaonan, Liu, Peng, Wang, Chao, Wei, Xuyong, Ding, Wei, Teng, Xiaodong, Xu, Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Biochemistry Cancer Cancer therapies Cell cycle Cell growth Chemotherapy Development and progression Drug resistance Fluorouracil Gastroenterology Glycoproteins Hepatology Hepatoma Hospitals Immunoglobulins Immunohistochemistry Laboratories Liver Liver cancer Medical prognosis Medicine Medicine & Public Health Oncology Original Original Article Prognosis Proteases Proteins Surgery Transplant Surgery Tumors Ubiquitin
Online-Zugang:	Volltext
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