Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study

Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome sequencing (WGS) has emerged as a 'one-st...

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Veröffentlicht in:	Microbial genomics 2020-02, Vol.6 (2)
Hauptverfasser:	Doyle, Ronan M, O'Sullivan, Denise M, Aller, Sean D, Bruchmann, Sebastian, Clark, Taane, Coello Pelegrin, Andreu, Cormican, Martin, Diez Benavente, Ernest, Ellington, Matthew J, McGrath, Elaine, Motro, Yair, Phuong Thuy Nguyen, Thi, Phelan, Jody, Shaw, Liam P, Stabler, Richard A, van Belkum, Alex, van Dorp, Lucy, Woodford, Neil, Moran-Gilad, Jacob, Huggett, Jim F, Harris, Kathryn A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteria - classification Bacteria - drug effects Bacteria - genetics Bacteria - isolation & purification Carbapenems - pharmacology Ciprofloxacin - pharmacology Computational Biology Drug Resistance, Bacterial Genome, Bacterial Humans Microbial Sensitivity Tests
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