Effect of brown adipose tissue activation on myocardial fluorine-18-fluorodeoxyglucose uptake
Abstract The aim of this study is to investigate the relationship between brown adipose tissue (BAT) activation and myocardial fluorine-18-fluorodeoxyglucose ([ 18 F] FDG) uptake in terms of intensity and patterns. The patients were divided into two groups as follows: BAT and control groups. The BAT...
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| Veröffentlicht in: | World journal of nuclear medicine 2020-01, Vol.19 (1), p.41-46 |
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| description | Abstract
The aim of this study is to investigate the relationship between brown adipose tissue (BAT) activation and myocardial fluorine-18-fluorodeoxyglucose ([
18
F] FDG) uptake in terms of intensity and patterns. The patients were divided into two groups as follows: BAT and control groups. The BAT group consists of 34 cases that showed BAT uptake. The control group, with no BAT uptake, included 68 patients who were matched for body mass index, gender, and season. The scans were retrospectively reviewed by two nuclear medicine physicians who visually evaluated the intensity of myocardial [
18
F] FDG uptake. The myocardial [
18
F] FDG uptake was visually classified into the following three patterns: diffuse, heterogeneous, and focal. The regions of activated BAT distribution were noted. The mean myocardial [
18
F] FDG uptake was 2.50 ± 0.75 for the BAT group and 2.13 ± 0.88 for the control group with a statistically significant difference (
P
= 0.031). The myocardial [
18
F] FDG uptake pattern was similar in the BAT and control groups with the diffuse pattern being the most common, followed by the heterogeneous and less commonly focal. In the BAT group, the anatomical distribution of BAT was mainly in supraclavicular, paravertebral, and axillary and to a lesser extent in cervical regions. BAT group had a significantly higher intensity of [
18
F] FDG myocardial uptake compared to that of the control group. The presence of activated BAT did not affect the pattern of myocardial uptake. Knowledge of these findings may help in understanding the variability of myocardial [
18
F] FDG uptake and consequently in avoiding misinterpretation of cardiac findings in positron-emission tomography/computed tomography studies. |
| doi_str_mv | 10.4103/wjnm.WJNM_16_19 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7067125</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A616136546</galeid><sourcerecordid>A616136546</sourcerecordid><originalsourceid>FETCH-LOGICAL-c530i-50e30db5b614d8d56351cc49d756464fa0bb14534f3680f67a28de519c9aa50d3</originalsourceid><addsrcrecordid>eNp1ks1v0zAYhyMEYtPYmRuKhIS4pLPj2EkuSNM0vjTgAuKELMd53bp17GInK_3vcZpuXRFLItlynvcX-82TJC8xmhUYkYvN0nazn5-_fuGYcVw_SU4xQ2VGCM6fxnlBUYZxUZ4k5yEsUbxoXpW0fJ6ckBzXCOX4NPl1rRTIPnUqbbzb2FS0eu0CpL0OYYBUyF7fil47m8an2zopfKuFSZUZnNcWMlxlu7lrwf3Zzs0gx_Jh3YsVvEieKWECnO_Hs-TH--vvVx-zm28fPl1d3mSSEqQzioCgtqENw0VbtZQRiqUs6rakrGCFEqhp4nFIoQirkGKlyKsWKK5lLQRFLTlL3k2566HpoJVgey8MX3vdCb_lTmh-_MbqBZ-7W14iVuKcxoC3-wDvfg8Qet7pIMEYYcENgeekrBGOO2ARff0PunSDt_F4I4XyitQ5OlBzYYBrq1z8rhxD-SXDDBNGd1mz_1DxbqHT0llQOq4fFbx5ULAAYfpFcGYYf1A4Bi8mUHoXggd13wyM-GgPH-3hB3tixauHPbzn71yJAJ-AjTM9-LAywwY8j-zKus1juXGRT45xp_jOMb53jE-O8TvHDu3oFxo6ODT2sT3_BRxk84w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2370283920</pqid></control><display><type>article</type><title>Effect of brown adipose tissue activation on myocardial fluorine-18-fluorodeoxyglucose uptake</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>Thieme Connect Journals Open Access</source><source>PubMed Central</source><creator>Alenezi, Saud A. ; Dannoon, Shorouk F. ; Alnafisi, Naheel S. ; Asa'ad, Saqr M. ; Osman, Medhat M. ; Elgazzar, Abdelhamid H.</creator><creatorcontrib>Alenezi, Saud A. ; Dannoon, Shorouk F. ; Alnafisi, Naheel S. ; Asa'ad, Saqr M. ; Osman, Medhat M. ; Elgazzar, Abdelhamid H.</creatorcontrib><description>Abstract
The aim of this study is to investigate the relationship between brown adipose tissue (BAT) activation and myocardial fluorine-18-fluorodeoxyglucose ([
18
F] FDG) uptake in terms of intensity and patterns. The patients were divided into two groups as follows: BAT and control groups. The BAT group consists of 34 cases that showed BAT uptake. The control group, with no BAT uptake, included 68 patients who were matched for body mass index, gender, and season. The scans were retrospectively reviewed by two nuclear medicine physicians who visually evaluated the intensity of myocardial [
18
F] FDG uptake. The myocardial [
18
F] FDG uptake was visually classified into the following three patterns: diffuse, heterogeneous, and focal. The regions of activated BAT distribution were noted. The mean myocardial [
18
F] FDG uptake was 2.50 ± 0.75 for the BAT group and 2.13 ± 0.88 for the control group with a statistically significant difference (
P
= 0.031). The myocardial [
18
F] FDG uptake pattern was similar in the BAT and control groups with the diffuse pattern being the most common, followed by the heterogeneous and less commonly focal. In the BAT group, the anatomical distribution of BAT was mainly in supraclavicular, paravertebral, and axillary and to a lesser extent in cervical regions. BAT group had a significantly higher intensity of [
18
F] FDG myocardial uptake compared to that of the control group. The presence of activated BAT did not affect the pattern of myocardial uptake. Knowledge of these findings may help in understanding the variability of myocardial [
18
F] FDG uptake and consequently in avoiding misinterpretation of cardiac findings in positron-emission tomography/computed tomography studies.</description><identifier>ISSN: 1450-1147</identifier><identifier>EISSN: 1607-3312</identifier><identifier>DOI: 10.4103/wjnm.WJNM_16_19</identifier><identifier>PMID: 32190021</identifier><language>eng</language><publisher>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India: Thieme Medical and Scientific Publishers Pvt. Ltd</publisher><subject>Activation ; Adipose tissue ; Advertising executives ; Age ; Body fat ; Body mass index ; Body size ; Cold ; Computed tomography ; Emission analysis ; Fatty acids ; Fluorides ; Fluorine ; Fluorine compounds ; Fluorine isotopes ; Heart ; Metabolism ; Nuclear medicine ; Original ; Original Article ; Patients ; Physicians ; Physiology ; Statistical analysis ; Studies</subject><ispartof>World journal of nuclear medicine, 2020-01, Vol.19 (1), p.41-46</ispartof><rights>Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon.</rights><rights>Copyright: © 2020 World Journal of Nuclear Medicine.</rights><rights>COPYRIGHT 2020 Medknow Publications and Media Pvt. Ltd.</rights><rights>2020. This work is published under https://creativecommons.org/licenses/by-nc-sa/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2020 World Journal of Nuclear Medicine 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067125/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067125/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,20890,27923,27924,53790,53792,54586,54614</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32190021$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Alenezi, Saud A.</creatorcontrib><creatorcontrib>Dannoon, Shorouk F.</creatorcontrib><creatorcontrib>Alnafisi, Naheel S.</creatorcontrib><creatorcontrib>Asa'ad, Saqr M.</creatorcontrib><creatorcontrib>Osman, Medhat M.</creatorcontrib><creatorcontrib>Elgazzar, Abdelhamid H.</creatorcontrib><title>Effect of brown adipose tissue activation on myocardial fluorine-18-fluorodeoxyglucose uptake</title><title>World journal of nuclear medicine</title><addtitle>World J Nucl Med</addtitle><description>Abstract
The aim of this study is to investigate the relationship between brown adipose tissue (BAT) activation and myocardial fluorine-18-fluorodeoxyglucose ([
18
F] FDG) uptake in terms of intensity and patterns. The patients were divided into two groups as follows: BAT and control groups. The BAT group consists of 34 cases that showed BAT uptake. The control group, with no BAT uptake, included 68 patients who were matched for body mass index, gender, and season. The scans were retrospectively reviewed by two nuclear medicine physicians who visually evaluated the intensity of myocardial [
18
F] FDG uptake. The myocardial [
18
F] FDG uptake was visually classified into the following three patterns: diffuse, heterogeneous, and focal. The regions of activated BAT distribution were noted. The mean myocardial [
18
F] FDG uptake was 2.50 ± 0.75 for the BAT group and 2.13 ± 0.88 for the control group with a statistically significant difference (
P
= 0.031). The myocardial [
18
F] FDG uptake pattern was similar in the BAT and control groups with the diffuse pattern being the most common, followed by the heterogeneous and less commonly focal. In the BAT group, the anatomical distribution of BAT was mainly in supraclavicular, paravertebral, and axillary and to a lesser extent in cervical regions. BAT group had a significantly higher intensity of [
18
F] FDG myocardial uptake compared to that of the control group. The presence of activated BAT did not affect the pattern of myocardial uptake. Knowledge of these findings may help in understanding the variability of myocardial [
18
F] FDG uptake and consequently in avoiding misinterpretation of cardiac findings in positron-emission tomography/computed tomography studies.</description><subject>Activation</subject><subject>Adipose tissue</subject><subject>Advertising executives</subject><subject>Age</subject><subject>Body fat</subject><subject>Body mass index</subject><subject>Body size</subject><subject>Cold</subject><subject>Computed tomography</subject><subject>Emission analysis</subject><subject>Fatty acids</subject><subject>Fluorides</subject><subject>Fluorine</subject><subject>Fluorine compounds</subject><subject>Fluorine isotopes</subject><subject>Heart</subject><subject>Metabolism</subject><subject>Nuclear medicine</subject><subject>Original</subject><subject>Original Article</subject><subject>Patients</subject><subject>Physicians</subject><subject>Physiology</subject><subject>Statistical analysis</subject><subject>Studies</subject><issn>1450-1147</issn><issn>1607-3312</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>0U6</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1ks1v0zAYhyMEYtPYmRuKhIS4pLPj2EkuSNM0vjTgAuKELMd53bp17GInK_3vcZpuXRFLItlynvcX-82TJC8xmhUYkYvN0nazn5-_fuGYcVw_SU4xQ2VGCM6fxnlBUYZxUZ4k5yEsUbxoXpW0fJ6ckBzXCOX4NPl1rRTIPnUqbbzb2FS0eu0CpL0OYYBUyF7fil47m8an2zopfKuFSZUZnNcWMlxlu7lrwf3Zzs0gx_Jh3YsVvEieKWECnO_Hs-TH--vvVx-zm28fPl1d3mSSEqQzioCgtqENw0VbtZQRiqUs6rakrGCFEqhp4nFIoQirkGKlyKsWKK5lLQRFLTlL3k2566HpoJVgey8MX3vdCb_lTmh-_MbqBZ-7W14iVuKcxoC3-wDvfg8Qet7pIMEYYcENgeekrBGOO2ARff0PunSDt_F4I4XyitQ5OlBzYYBrq1z8rhxD-SXDDBNGd1mz_1DxbqHT0llQOq4fFbx5ULAAYfpFcGYYf1A4Bi8mUHoXggd13wyM-GgPH-3hB3tixauHPbzn71yJAJ-AjTM9-LAywwY8j-zKus1juXGRT45xp_jOMb53jE-O8TvHDu3oFxo6ODT2sT3_BRxk84w</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Alenezi, Saud A.</creator><creator>Dannoon, Shorouk F.</creator><creator>Alnafisi, Naheel S.</creator><creator>Asa'ad, Saqr M.</creator><creator>Osman, Medhat M.</creator><creator>Elgazzar, Abdelhamid H.</creator><general>Thieme Medical and Scientific Publishers Pvt. 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The aim of this study is to investigate the relationship between brown adipose tissue (BAT) activation and myocardial fluorine-18-fluorodeoxyglucose ([
18
F] FDG) uptake in terms of intensity and patterns. The patients were divided into two groups as follows: BAT and control groups. The BAT group consists of 34 cases that showed BAT uptake. The control group, with no BAT uptake, included 68 patients who were matched for body mass index, gender, and season. The scans were retrospectively reviewed by two nuclear medicine physicians who visually evaluated the intensity of myocardial [
18
F] FDG uptake. The myocardial [
18
F] FDG uptake was visually classified into the following three patterns: diffuse, heterogeneous, and focal. The regions of activated BAT distribution were noted. The mean myocardial [
18
F] FDG uptake was 2.50 ± 0.75 for the BAT group and 2.13 ± 0.88 for the control group with a statistically significant difference (
P
= 0.031). The myocardial [
18
F] FDG uptake pattern was similar in the BAT and control groups with the diffuse pattern being the most common, followed by the heterogeneous and less commonly focal. In the BAT group, the anatomical distribution of BAT was mainly in supraclavicular, paravertebral, and axillary and to a lesser extent in cervical regions. BAT group had a significantly higher intensity of [
18
F] FDG myocardial uptake compared to that of the control group. The presence of activated BAT did not affect the pattern of myocardial uptake. Knowledge of these findings may help in understanding the variability of myocardial [
18
F] FDG uptake and consequently in avoiding misinterpretation of cardiac findings in positron-emission tomography/computed tomography studies.</abstract><cop>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India</cop><pub>Thieme Medical and Scientific Publishers Pvt. Ltd</pub><pmid>32190021</pmid><doi>10.4103/wjnm.WJNM_16_19</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; Thieme Connect Journals Open Access; PubMed Central |
| subjects | Activation Adipose tissue Advertising executives Age Body fat Body mass index Body size Cold Computed tomography Emission analysis Fatty acids Fluorides Fluorine Fluorine compounds Fluorine isotopes Heart Metabolism Nuclear medicine Original Original Article Patients Physicians Physiology Statistical analysis Studies |
| title | Effect of brown adipose tissue activation on myocardial fluorine-18-fluorodeoxyglucose uptake |
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