Adhesion between P. falciparum infected erythrocytes and human endothelial receptors follows alternative binding dynamics under flow and febrile conditions

Characterizing the adhesive dynamics of Plasmodium falciparum infected erythrocytes (IEs) to different endothelial cell receptors (ECRs) in flow is a big challenge considering available methods. This study investigated the adhesive dynamics of IEs to five ECRs (CD36, ICAM-1, P-selectin, CD9, CSA) us...

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Veröffentlicht in:	Scientific reports 2020-03, Vol.10 (1), p.4548-4548, Article 4548
Hauptverfasser:	Lubiana, Pedro, Bouws, Philip, Roth, Lisa Katharina, Dörpinghaus, Michael, Rehn, Torben, Brehmer, Jana, Wichers, Jan Stephan, Bachmann, Anna, Höhn, Katharina, Roeder, Thomas, Thye, Thorsten, Gutsmann, Thomas, Burmester, Thorsten, Bruchhaus, Iris, Metwally, Nahla Galal
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/417/1716 631/326/417/2547 Adhesion Bioinformatics Bronchi - metabolism Bronchi - parasitology CD36 antigen CD36 Antigens - metabolism CD9 antigen Cell Adhesion Cells, Cultured Endothelial cells Endothelium, Vascular - metabolism Endothelium, Vascular - parasitology Erythrocytes Erythrocytes - metabolism Erythrocytes - parasitology Fever Humanities and Social Sciences Humans Intercellular adhesion molecule 1 Intercellular Adhesion Molecule-1 - metabolism Malaria Malaria, Falciparum - metabolism Malaria, Falciparum - parasitology multidisciplinary P-selectin P-Selectin - metabolism Parasites Plasmodium falciparum Plasmodium falciparum - isolation & purification Plasmodium falciparum - metabolism Receptors, Cell Surface - metabolism Science Science (multidisciplinary) Vector-borne diseases
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