HIV-1 gp120-CD4i Antibody Complex Elicits CD4 Binding Site Specific Antibody Response in Mice

Elicitation of broadly neutralizing antibody (bNAb) responses toward the conserved HIV-1 Envelope (Env) CD4 binding site (CD4bs) by vaccination is an important goal for vaccine development and yet to be achieved. The outcome of previous immunogenicity studies suggests that the limited accessibility...

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Veröffentlicht in:	The Journal of immunology (1950) 2020-02, Vol.204 (6), p.1543-1561
Hauptverfasser:	Galkin, Andrey, Chen, Yajing, Guenaga, Javier, O’Dell, Sijy, Acevedo, Roderico, Steinhardt, James J., Wang, Yimeng, Wilson, Richard, Chiang, Chi-I, Doria-Rose, Nicole, Grishaev, Alexander V., Mascola, John R., Li, Yuxing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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